Denisova Genome

Public Data Sets>Denisova Genome
The high-coverage genome sequence of a Denisovan individual sequenced to ~30x coverage on the Illumina platform. Together with their sister group the Neandertals, Denisovans are the most closely related extinct relatives of currently living humans.

Details

Submitted By: Adam Gray
US Snapshot ID (Linux/Unix): snap-d04dd2b7 (US East, Bam Files)
Size: 159 GiB
License: Following the Ft. Lauderdale principles on Community Resource Projects (see details below)
Source: The Max Planck Institute for Evolutionary Anthropology
Created On: February 6, 2012 8:00 AM GMT
Last Updated: February 15, 2012 2:22 AM GMT

EBS Snapshots:

  • US East, Bam Files (159 GiB): snap-d04dd2b7
  • US East, FastQ Files (316 GiB): snap-8099f7e7
  • EU West, Bam Files (159 GiB): snap-3cc2de54
  • EU West, FastQ files (316 GiB): snap-29cd2942

    The genome sequence of a Denisovan individual was generated from a small fragment of a finger bone discovered in Denisova Cave in southern Siberia in 2008. Approximately 30-fold coverage of the genome was generated using the Illumina GAIIx sequencing platform.

    The Denisova Genome Consortium have chosen to release the raw sequence data and alignments for the additional sequence generated for the Denisova phalanx (http://www.nature.com/nature/journal/v468/n7327/full/nature09710.html) in the expectation that these data will be a valuable resource for the research community. Provided here are the alignments using BWA to the human (hg19/GRCh37) and chimpanzee (panTro2) genomes.

    In keeping with the Ft. Lauderdale principles, the data are available for use, but users are expected to allow the data producers to make the first presentations and to publish the first paper containing genome-wide analyses of the data. Researchers who use small amounts of the data (eg: for single locus analyses) are not required to request permission. Researchers who have queries about whether they may present or submit Denisova genome data for publication may contact Svante Paabo.

    When using the Denisova genome data is it best to cite our most recent publication:

    Reich D, Green RE, Kircher M, Krause J, Patterson N, Durand EY, Viola B, Briggs AW, Stenzel U, Johnson PL, Maricic T, Good JM, Marques-Bonet T, Alkan C, Fu Q, Mallick S, Li H, Meyer M, Eichler EE, Stoneking M, Richards M, Talamo S, Shunkov MV, Derevianko AP, Hublin JJ, Kelso J, Slatkin M, Paabo S: Genetic history of an archaic hominin group from Denisova Cave in Siberia. Nature 2010, 468:1053-1060.
    Data and additional information are also provided from the project website at the Max Planck Institute for Evolutionary Anthropology at http://www.eva.mpg.de/denisova/

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