AWS HPC Blog
Author: Aniket Deshpande
Aniket Deshpande is senior GTM specialist for HPC in Healthcare Lifesciences at AWS. Aniket has more than a decade of experience in the biopharma and clinical informatics space, where he has developed and commercialized clinical-grade software solutions and services for genomics, molecular diagnostics, and translational research. Prior to AWS, Aniket has worked in various technical roles at DNAnexus, Qiagen, Knome, Pacific Biosciences and Novartis.
Benchmarking NVIDIA Clara Parabricks Somatic Variant Calling Pipeline on AWS
Somatic variants are genetic alterations which are not inherited but acquired during one’s lifespan, for example those that are present in cancer tumors. In this post, we will demonstrate how to perform somatic variant calling from matched tumor and normal genome sequence data, as well as tumor-only whole genome and whole exome datasets using an NVIDIA GPU-accelerated Parabricks pipeline, and compare the results with baseline CPU-based workflows.