AWS HPC Blog
Author: Stefan Dittforth
Stefan Dittforth is a Senior Healthcare Solutions Architect at AWS. He enjoys developing ideas to solve the many challenges the healthcare industry faces. One by one. When not burning his fingers on the soldering iron in a personal electronics project, you might find him enjoying the many cycle paths in the desert around Dubai.
Benchmarking the Oxford Nanopore Technologies basecallers on AWS
Oxford Nanopore sequencers enables direct, real-time analysis of long DNA or RNA fragments. They work by monitoring changes to an electrical current as nucleic acids are passed through a protein nanopore. The resulting signal is decoded to provide the specific DNA or RNA sequence by virtue of compute-intensive algorithms called basecallers. This blog post presents the benchmarking results for two of those Oxford Nanopore basecallers — Guppy and Dorado — on AWS. This benchmarking project was conducted in collaboration between G42 Healthcare, Oxford Nanopore Technologies and AWS.