NITRC-CE is a virtual computing platform pre-configured with many neuroimaging data analysis applications. Use NITRC-CE Classic instead of NITRC-CE LITE when you use many system-installed software packages to save time loading and maintaining versioning including: 3D Slicer, AFNI, ANTS, BrainSuite, CONN, Connectome Workbench, Connectome Viewer, C-PAC, DataLad, Docker, DTIPrep, FreeSurfer, FSL, gradunwarp, HCP Pipelines, HeuDiConv, LONI Pipeline Environment, MaCH, MRIcron, MRtrix, NeuroDocker, NEURON, PLINK!, Pydicom, DIPY, NiBabel, NIPY, NiPype, Singularity, SOLAR-Eclipse, SPM, and TrackVis. Leveraging NeuroDebian, NITRC-CE joins the family of successful NITRC services starting with the flagship, NITRC-Resources, the "go to" place for neuroimaging tools and resources. NITRC Image Repository offers a select set of community-generated neuroimaging data sets, while this service, NITRC Computational Environment, offers the convenience of cloud-based computing against NITRC-IR data sets or your data sets. We welcome any suggestions on how to improve this service to make it a user friendly tool for neuroscientists to easily and cost-effectively compute against data sets.