Analyze more than 800,000 long reads of genomic data (about 102 GB) in 3 hours thanks to Huxelerate Hugenomic Nanopolish(*).

Huxelerate Hugenomic Nanopolish enables ultra-fast signal-level analysis of large datasets of Oxford Nanopore Sequencing data.

This AMI is a CentoOS Linux image and comes pre-installed with Hugenomic Nanopolish developed by Huxelerate. The software is based on Nanopolish (see Resources section for reference) and can calculate an improved consensus sequence for a draft genome assembly, detect base modifications, call SNPs and indels with respect to a reference genome and more.

The accelerated implementation exploits FPGAs to accelerate the computation and provide high performance and faster time to result. The current implementation allows to accelerate the eventalign tool, reducing computational time from days to hours when compared to software-only executions on AWS.

The functionalities provided in this release, mirror Nanopolish v0.13.2.

Huxelerate supports academic research. If you are willing to use this AMI for your academic research, please contact us at info@huxelerate.it .

(*) dataset coming from the WGS consortium (see Resources section for reference)
flowcell_id FAB42451
reads 818,420
bases 5,228,838,859
mean 6389
n50 10,490
Original Nanopolish tested on C4.8xlarge using 36 cores took 17,25 hours