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- Guidance for Scalable Cryo-EM on AWS Parallel Computing Service (PCS)
Guidance for Scalable Cryo-EM on AWS Parallel Computing Service (PCS)
Overview
This guidance shows how to deploy a secure, high-performance Cryo-EM analysis environment on AWS ParallelCluster Service, enabling research organizations to accelerate molecular structure determination. By combining CryoSPARC software with flexible CPU/GPU compute options, high-throughput FSx storage, and automated Slurm job management, researchers can efficiently process large-scale Cryo-EM datasets through a secure web interface. The solution streamlines deployment while providing the computational power and storage performance needed for advanced structural biology research.
Benefits
Deploy purpose-built high-performance computing infrastructure for Cryo-EM research without managing complex hardware. Researchers can focus on breakthrough science while AWS PCS automatically provisions the right compute resources for each processing stage.
Scale computing resources dynamically based on workload demands with purpose-designed instance groups for CPU and GPU processing. Pay only for the computational power you need when you need it, eliminating idle infrastructure costs during research cycles.
Access high-throughput storage with FSx for Lustre and EFS to efficiently process and store large microscopy datasets. The integrated storage solution provides researchers with seamless data management from initial capture through processing to long-term archival in S3.
How it works
These technical details feature an architecture diagram to illustrate how to effectively use this solution. The architecture diagram shows the key components and their interactions, providing an overview of the architecture's structure and functionality step-by-step.
Deploy with confidence
Ready to deploy? Review the sample code on GitHub for detailed deployment instructions to deploy as-is or customize to fit your needs.
Disclaimer
The sample code; software libraries; command line tools; proofs of concept; templates; or other related technology (including any of the foregoing that are provided by our personnel) is provided to you as AWS Content under the AWS Customer Agreement, or the relevant written agreement between you and AWS (whichever applies). You should not use this AWS Content in your production accounts, or on production or other critical data. You are responsible for testing, securing, and optimizing the AWS Content, such as sample code, as appropriate for production grade use based on your specific quality control practices and standards. Deploying AWS Content may incur AWS charges for creating or using AWS chargeable resources, such as running Amazon EC2 instances or using Amazon S3 storage.
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