AWS Public Sector Blog
Author: Noora Siddiqui
Noora Siddiqui is a life scientist turned cloud engineer at the Baylor College of Medicine Human Genome Sequencing Center. She pioneered the design, development, and implementation of a clinical genomics pipeline in the cloud and has worked on large-scale, multi-center studies driving innovation in diagnostics and precision medicine. Prior to joining Baylor College of Medicine, Noora was a graduate student specializing in the use of high-performance computing to explore problems in drug discovery and clinical bioinformatics. She is passionate about education, mentorship, and building solutions at the nexus of healthcare and technology.
Building a resilient and scalable clinical genomics analysis pipeline with AWS
At the Baylor College of Medicine Human Genome Sequencing Center (BCM HGSC), we aim to advance precision medicine and research in genomics. In that effort, we joined the ambitious All of Us Research Program funded by the National Institutes of Health (NIH) to help deliver genomic data to over one million individuals across the United States. In early 2019, we estimated that processing whole genome samples for this megaproject would imply a scale-up of over four times the production workload of our center. We used AWS to support our new pipeline demands, which saved time, reduced costs, and created new opportunities for future development.