AWS Public Sector Blog

Tag: Enterome

Drug Discovery and Biomarkers Development on the Human Gut Microbiome Using AWS Batch and Nextflow

Gut microbiome plays a critical role in building our immune system at birth. It provides a life-long personal and natural protection. To fully explore and characterize the role of the human gut microbiome, Enterome uses different approaches, including the latest genome sequencing technologies, to reconstruct microbial genomes and quantify the abundance of different species and microbial genes in the gut across large cohorts of patients. The current high throughput sequencing technologies produce tens of millions of DNA sequences for each biological sample and the human gut microbiome is estimated to contain hundreds of species and several million unique bacterial genes that can be identified and analyzed. Enterome’s mission is to translate all of this information into actual knowledge, which can be applied to advanced clinical and drug discovery programs.