Powering the future of children’s health: AWS announces the 2025 Children’s Health Innovation Award recipients

Today, on National Child Health Day, Amazon Web Services (AWS) is proud to announce the recipients of the 2025 AWS Imagine Grant Children’s Health Innovation Award (CHIA). This year’s cohort recognizes nine leading healthcare, research, and humanitarian organizations who are using AWS to realize a common vision: creating a world where every child has the opportunity to thrive through innovative solutions that predict, prevent, and address health challenges.

The 2025 CHIA recipients are: the American Academy of Pediatrics (AAP), Boston Children’s Hospital, Children’s Hospital Association, HudsonAlpha Institute for Biotechnology, Nationwide Children’s Hospital, Operation Smile, Pediatric Brain Tumor Foundation, Phoenix Children’s Hospital, and Save the Children.

Recipient organizations use AWS to improve clinical treatment outcomes and enhance disease prevention for children globally

The 2025 CHIA recipients are using AWS solutions in several innovative ways, including applying advanced generative AI and machine learning solutions to transform clinical decision-making with data-driven tools. Boston Children’s “Clinical Doppelgängers” project uses generative AI to analyze thousands of patient cases and millions of data points, delivering physicians real-time, evidence-based decision support for pediatric care.

Nationwide Children’s “GENIUS” is an AI-powered platform that identifies which infants need rapid genome sequencing, automates complex interpretation, and keeps re-checking past cases as new science emerges—seamlessly integrated into electronic medical records (EMR) and powered by Amazon Bedrock. By getting the right test to the right child sooner, “GENIUS” aims to cut diagnostic delays by more than half and double the number of neonatal intensive care unit (NICU) patients who receive a genetic diagnosis within two weeks. HudsonAlpha’s new variant analysis platform is accelerating rare disease diagnosis through automated genomic analysis. Their solution will provide a scalable and collaborative platform to more quickly and effectively diagnose rare genetic diseases, especially those affecting children.

The power of predictive analytics is also reshaping preventive care. Save the Children’s disease AI-powered surveillance system in Bangladesh is moving beyond passive monitoring to forecast disease outbreaks with a multilingual voice assistant for healthcare workers, targeting early intervention in conditions like pneumonia and diarrhea. Phoenix Children’s Hospital’s venous thromboembolism (VTE) solution helps identify at-risk patients before complications arise. These projects share common threads: they use AWS to analyze large datasets, make predictions, and deliver insights at scale.

Fostering collaboration and system-wide improvements are key outcomes

At the heart of this transformation is also democratization of health access. AAP seeks to improve pediatric care nationally through innovative data strategy efforts. Their solution, created with contributions from pediatricians and family partners, will incorporate de-identified data from health records from across the country to understand best practices and gaps in care to promote health equity. The Pediatric Brain Tumor Foundation’s multilingual clinical trial navigator simplifies the complex process of finding and understanding clinical trials, making critical treatment options accessible to all families. Operation Smile is using AWS Supply Chain solutions to optimize its supply centers across 117 partner hospitals worldwide, ensuring faster delivery of critical medical supplies to treat children with cleft conditions.

These initiatives are built on a foundation of collaborative innovation, exemplified by the Children’s Hospital Association’s “Child Health Learning Platform.” Their comprehensive data ecosystem will connect 220 children’s hospitals, enabling unprecedented research and analytics capabilities.

By combining cloud technology, generative AI, and cross-institutional collaboration, the 2025 CHIA recipients are building a future where every child has access to the best possible care, informed by the latest data and delivered with precision and compassion.

About the Children’s Health Innovation Award

Now in year two of a three-year, $10 million commitment by AWS to advancing children’s health outcomes, CHIA recipient organizations will receive a total of over $2.5 million in cash funding and AWS computing credits, alongside expert technical guidance, to advance their projects.

To learn more about each organization’s vision in more detail, visit the AWS Imagine Grant CHIA webpage and sign up to be notified about future cycles.