AWS for Industries

Transform healthcare prior authorization with AI Agents

Prior authorization represents one of healthcare’s most persistent operational challenges, creating friction between necessary care oversight and timely patient treatment. This critical process requires healthcare providers to obtain approval from insurance payors before delivering specific medical services, medications, or procedures. The 2024 AMA survey of 1,000 practicing physicians reveals that 93% report care delays due to prior authorization. It also indicates that 82% of patients at least sometimes abandon their recommended treatment due to these barriers.

We will demonstrate how Amazon Bedrock AgentCore transforms this traditionally manual, error-prone process into an intelligent, automated process that accelerates care delivery workflows while maintaining compliance and accuracy. Through a real patient journey, we’ll explore how multi-agent AI solution can reduce prior authorization processing time from days to minutes. Our solution can fundamentally improve both operational efficiency and patient experience.

The healthcare operations challenge

Traditional healthcare workflows face several critical operational challenges that directly impact patient care and healthcare economics:

  • Manual documentation burden: Healthcare staff spend countless hours collecting, organizing, and submitting required clinical documentation. Each case requires gathering patient records, clinical notes, diagnostic results, and treatment justifications from multiple systems and sources.
  • Appointment scheduling complexity: Coordinating appointments for procedures requiring prior authorization creates additional administrative overhead. Staff must manage scheduling dependencies, communicate authorization status to patients, and reschedule appointments based on approval timelines, often leading to fragmented patient experiences.
  • Payor-specific complexity: Each insurance provider maintains different requirements, forms, and submission processes. Administrative teams must navigate varying documentation standards, approval criteria, and communication protocols across dozens of different payors.
  • Limited visibility and communication gaps: Traditional workflows provide minimal real-time visibility into approval status, creating uncertainty for patients and providers. Status updates are often delayed, incomplete, or require manual follow-up calls.
  • Treatment delays: These inefficiencies directly impact patient care through treatment delays, with studies showing that physicians and their staff spend nearly two business days each week on prior authorization requests, potentially affecting patient outcomes and satisfaction.

A patient’s journey

To help make this more applicable, we have designed a demonstration that follows a patient’s typical journey.

A patient discovered a suspicious mass during their routine mammogram. Their radiologist recommended an immediate diagnostic procedure—a case requiring prior authorization from their insurance provider. In traditional workflows, this would trigger days of manual processes including clinical documentation collection, payor-specific form completion, and status monitoring, while the patient anxiously awaits clearance.

Instead, this patient’s experience will showcase the transformative power of AI-driven automation. From the moment the radiologist enters the biopsy order into the electronic health record (EHR), intelligent agents will begin orchestrating the entire prior authorization workflow behind the scenes. They will confirm rapid processing, while maintaining clinical accuracy and regulatory compliance.

Solution: Multi-agent healthcare operations architecture

Let’s dive into implementing the solution harnessing Amazon Bedrock AgentCore to deploy a system of specialized AI agents, each designed to handle specific aspects of the prior authorization workflow as demonstrated in Figure 1. This distributed approach enables parallel processing, reduces bottlenecks, and facilitates comprehensive coverage of all authorization requirements.

Following are the workflow steps depicted in the diagram:

1.Data ingestion: The workflow begins when a patient’s data enters the system through one of multiple integrated pathways:

  1. AWS HealthLake: Serves as the central repository for FHIR-compliant clinical data. It securely stores structured patient records, diagnostic information, treatment histories, and procedural documentation in standardized healthcare formats—enabling seamless interoperability across systems.
  2. Amazon Simple Storage Service (Amazon S3): Provides scalable, secure storage infrastructure for unstructured medical documentation including clinical images, PDF reports, handwritten notes, and legacy documents. It features automated classification and indexing capabilities that make patient information accessible to AI agents.

This dual-layer data architecture confirms that both structured clinical data and unstructured medical documents are available to the AI agents. With this access, comprehensive analysis and complete documentation assembly for prior authorization requests can occur without manual intervention.

2. Appointment scheduling: The appointment management system serves as a critical entry point for the patient journey, utilizing Amazon Connect, Amazon Lex, and Amazon Q to facilitate seamless appointment scheduling. When providers schedule appointments for procedures requiring prior authorization, the solution automatically triggers the authorization workflow. It facilitates integrated care coordination and efficient management of clinical information for timely and accurate patient care. This integration eliminates the traditional disconnect between scheduling and authorization processes.

3. Ambient listening: AWS HealthScribe is integrated to record and transcribe patient-clinician conversations, providing a reliable solution for documenting and storing clinical notes—improving care coordination and documentation.

4. Prior authorization orchestration: When a patient’s care provider enters the prior authorization order (often triggered by the appointment scheduling process), the automated sequence completes in under 10 minutes using Amazon Bedrock AgentCore.

  • Step 1: Order detection and initiation: The Prior Authorization Orchestrator Agent detects the new order in the EHR system and automatically initiates the prior authorization workflow. It identifies required documentation and payor-specific requirements.
  • Step 2: Eligibility verification: The Eligibility Verification Agent performs real-time checks against the patient’s insurance provider. It confirms active coverage, identifies specific authorization requirements, and determines if prior authorization is required and the appropriate submission pathway.
  • Step 3: Clinical documentation assembly: The Document Processing Agent automatically collects and organizes clinical notes from the patient’s appointment and diagnostic reports detailing findings. It also gathers relevant patient medical history and risk factors, as well as current insurance information and coverage details.
  • Step 4: Authorization submission: The Prior Authorization Agent completes the payer-specific authorization form using the assembled clinical data. It submits the request through the appropriate electronic, or manual, channel based on payer requirements.

5. Continuous monitoring and updates (ongoing): The solution continuously monitors authorization status and automatically sends updates to all stakeholders, including the patient, physician, and scheduling staff.

Conclusion

The multi-agent AI framework powered by Amazon Bedrock AgentCore directly confronts these systemic inefficiencies, transforming a process that consumes hours of physician’s time each week into an automated workflow completed in minutes. It eliminates manual documentation tasks, accelerates approval processes, and facilitates complete, accurate submissions. This intelligent automation reduces denial rates and treatment delays, while fundamentally redefining healthcare delivery as truly patient-centric.

The healthcare industry will continue its evolution toward value-based care models with AI-driven solutions. Technology like this demonstrates how it can preserve the essential human elements of healthcare, while removing the administrative friction that too often stands between patients and the care they need. The future of healthcare operations can be more efficient and more human.

Contact an AWS Representative to find out how we can help accelerate your business.


Further reading

TAGS:
Manish Patel

Manish Patel

Manish Patel is a Global Solutions Architect at AWS with 20+ years of experience supporting Healthcare and Life Sciences customers. He drives strategies with partners to accelerate development of multi-model data solutions, generative AI, EHR and medical imaging. He is passionate about using technology to transform the industry for better patient outcomes.

Vikash Gupta

Vikash Gupta

Vikash Gupta, PhD, CIIP serves as a Senior AI/ML Solutions Architect on the AWS Global Healthcare and Life Sciences team, leveraging his 15+ years of radiology workflow expertise to architect transformative healthcare solutions. He is dedicated to democratizing healthcare access through cloud computing, with a particular focus on bringing quality medical services to underserved rural communities worldwide.

Laks Sundararajan

Laks Sundararajan

Laks Sundararajan is a seasoned Enterprise Architect helping companies reset, transform and modernize their IT, digital, cloud, data and insight strategies. A proven leader with significant expertise around Generative AI, Digital, Cloud and Data/Analytics Transformation, Laks is a Sr. Solutions Architect with Healthcare and Life Sciences (HCLS).

Ramakant Joshi

Ramakant Joshi

Ramakant Joshi is an AWS Solutions Architect, specializing in the analytics and serverless domain. He has a background in software development and hybrid architectures, and is passionate about helping customers modernize their cloud architecture.