Henry Schein One and AWS leverage generative AI to revolutionize dentistry

Dental AI should streamline workflows, not create downtime. Henry Schein One and Amazon Web Services (AWS) are currently collaborating on the dental industry’s first AI-augmented practice management system to master clinical capacity optimization. Let’s explore how this new AI-infused roadmap will change the industry.

Core deliverables and strategic intent

Henry Schein One is a leading provider of dental practice management solutions with a focus on the deep integration of generative AI capabilities across the Henry Schein One portfolio. They want to help move the industry from merely digital practice management to intelligent practice management.

“AI is no longer a future promise—it’s a present reality transforming how care is delivered. By collaborating with Henry Schein One, we are together leveraging generative AI to streamline documentation, personalize patient engagement, and reduce errors, while also tackling the harder challenges of adoption, like earning clinician trust and achieving equitable access. This is how technology becomes a true partner in improving outcomes across every corner of healthcare,” says Dr. Christine Tsien Silvers, MD, PhD, Healthcare Executive Advisor at AWS.

The primary objective of the collaboration is to eliminate the documentation burden, a major contributor to clinician burnout. This is achieved by leveraging Amazon Transcribe Medical and Amazon Bedrock to power a future Voice Notes feature, which will enable hands-free documentation.

The expected outcome is significant with early pilot results indicating:

• A projected 65-70% reduction in clinical documentation time
• A directly restored clinical focus to patient care while providing high-fidelity
• Comprehensive clinical notes

In operations, the strategy is to inject predictive and automated intelligence into core business functions. Utilizing Amazon Bedrock AgentCore, autonomous generative AI agents will be deployed to manage complex, administrative workflows.

These intelligent agents will deliver proactive capabilities, including:

• Predicting patient no-shows
• Automating claims validation
• A streamlined, accelerated revenue cycle

Finally, the goal is to elevate the standard of care by empowering clinicians with real-time, evidence-based data. The solution is being engineered to safely and securely analyze patient data at scale, resulting in synthesized evidence-based recommendations. It will support accurate diagnosis and optimize treatment planning, facilitating consistent, high-quality clinical outcomes across the network.

Security and compliance-first architecture

Deployment of this next-generation solution will be governed by a security and compliance-first architecture—a mandate for handling protected health information (PHI) at scale. Voice Notes is being built on an AWS HIPAA-compliant foundation and integrates specialized generative AI security tools. The core system leverages Amazon Nova Pro foundation models using Amazon Bedrock, specifically built with enterprise security features and HIPAA compliance standards.

Importantly, with AWS generative AI services, customer prompts and completions are never used to train any models, confirming complete data privacy. Amazon Bedrock AgentCore will provide the agentic platform required for secure, complex workflow management. Furthermore, data integrity will be maintained with all data being encrypted in transit and at rest using AWS Key Management Service (AWS KMS). Amazon Bedrock Guardrails will filter sensitive information while AWS Identity and Access Management (IAM) controls facilitate authorized access only. Voice Notes will integrate with Amazon CloudWatch and AWS CloudTrail for comprehensive logging, required for auditing and compliance verification.

The solution

This innovative solution utilizes a modern, cloud-native architecture built entirely on AWS managed services, ensuring exceptional scalability, reliability, and cost-effectiveness once deployed. Leveraging the agentic core framework previously described, the solution enables intelligent orchestration of AI workflows through Amazon Bedrock, allowing autonomous decisions about processing paths and quality validation.

The solution architecture is designed around five core principles that provide both technical excellence and business value:

1. Serverless-first approach: Optimizes operational efficiency by leveraging AWS managed services that automatically handle scaling, patching, and maintenance.
2. Event-driven design: Enables asynchronous processing, allowing the solution to handle high volumes of concurrent requests without performance degradation.
3. Microservices architecture: Facilitates loose coupling between components, enabling independent deployment and scaling of individual services.
4. Security by design: HIPAA compliance requirements are addressed through encryption, access controls, and audit logging built into every layer of the architecture.
5. Cost optimization: Leverages pay-as-you-go pricing models to verify costs scale linearly with usage, while eliminating infrastructure overhead.

Figure 1 – High-level solution architecture

Implementation acceleration and the role of Pariveda

This solution is being co-developed with key members of the AWS Partner Network, including consulting partner Pariveda Solutions Inc. The role of Pariveda as the implementation partner is critical, their expertise will help accelerate deployment. They will simultaneously verify the resulting solution is clinically sound, scalable, and that it is built to the highest Well-Architected and compliance standards. This consulting approach provides a model implementation blueprint—a tested, reliable strategy for other healthcare providers looking to rapidly and responsibly adopt generative AI at scale within a secure, compliant framework.

The AWS-Pariveda partnership creates a unified team structure that combines the deep cloud expertise of AWS with the implementation excellence of Pariveda. AWS provides architectural guidance, service optimization, and ongoing support, while Pariveda delivers rapid development cycles and proven project management methodologies. This collaboration accelerates time-to-market while reducing implementation risk through proven methodologies and extensive AWS service expertise.

Commitment to global impact

With Henry Schein One serving over 75,000 dental practices worldwide, this collaboration leverages the scalability and security of AWS to set a new global standard for generative AI-augmented dental care delivery. The solution will deliver technology that provides measurable operational efficiencies and improved patient outcomes.

“This collaboration represents a pivotal moment for dentistry,” said Ryan Hungate, Chief Clinical and Strategy Officer at Henry Schein One. “Cutting-edge AI is finally meeting clinical expertise. We’re not just improving workflows—we’re reimagining how dental care is delivered, documented, and optimized around the world. Our vision is to create an AI-first ecosystem that supports every aspect of care—from diagnostics to documentation, from claims to patient engagement—integrating intelligence into the core of every experience. This is the future of dentistry: connected, efficient, and profoundly human.”
The collaboration demonstrates the commitment AWS has to transforming healthcare through intelligent automation, while maintaining the highest standards of security, compliance, and clinical accuracy across a global network of dental practices.

Looking to the future

The future of healthcare is intelligent and secure. By building on the foundation of AWS, Henry Schein One will be setting the standard for dental innovation and establishing a roadmap for augmented healthcare delivery. This collaboration represents only the beginning of how AWS and Henry Schein One are reimagining dental practice management through generative AI.

Looking ahead, the partnership will continue to expand AI capabilities across the dental care industry, exploring new applications for predictive analytics, automated workflows, and intelligent patient engagement. The success of this implementation will provide a proven blueprint for other healthcare organizations seeking to responsibly adopt generative AI at scale, while maintaining strict compliance and security standards.

Explore how generative AI on AWS can transform your clinical workflows with a compliance-first approach. To learn more about Henry Schein One healthcare solutions, visit Henry Schein One. To learn more about how AWS can help your healthcare enterprise meet its goals, visit AWS for Healthcare & Life Sciences or speak with an AWS Representative.

Further reading

• Revolutionize personalized radiology learning using AI and AWS
• Building Trustworthy AI agents with Amazon Bedrock AgentCore Observability
• Breaking down healthcare’s walls with agentic AI

About Henry Schein One

Henry Schein One is a leading provider of dental practice management solutions, dedicated to enhancing the efficiency and effectiveness of dental practices worldwide. With a comprehensive suite of software and services, Henry Schein One empowers dental professionals to deliver exceptional patient care while streamlining their business operations. New AI solutions are designed to integrate seamlessly with existing workflows, providing practitioners with the tools they need to succeed in an ever-evolving healthcare landscape. By leveraging cutting-edge technology and a deep understanding of the dental industry, Henry Schein One is committed to driving growth, improving patient outcomes, and setting new standards for excellence in dental practice management.