Whitepapers, eBooks, and Infographics

Infographic: Improve energy efficiency with HPC from AWS and NVIDIA

Energy prices and consumption are growing, while data centers are experiencing power limitations. At the same time the increasing dataset sizes and pressure to deliver results are driving the need for more higher-performance HPC clusters.

Whitepaper: Optimizing HPC workloads with Amazon EC2 instances

Different EC2 instances are optimized for a range of workloads. Read this paper to learn how you can identify the right EC2 instance to maximize the performance of your HPC application.

Solution Brief: Driving energy efficiency for HPC workloads with accelerated computing from AWS and NVIDIA

Organizations around the world are using AWS and NVIDIA to run their HPC and AI/ML workloads. Powered by the latest NVIDIA GPUs and accelerated by various tools and services, organizations can gain insights faster while improving energy efficiency. Read this solution brief for an energy efficient approach to running these workloads at scale.

Infographic: Improve speed and accuracy in data-intensive HPC workloads powered by Intel Scalable processors

Amazon EC2 Hpc6id instances, powered by 3rd Gen Intel Xeon Scalable processors, provide attractive price-performance, memory, and local NVMe storage capabilities to help run your most data-intensive workloads more cost-effectively.  

Infographic: Accelerate discovery with virtually unlimited HPC infrastructure 

Leverage high performance computing (HPC) on AWS powered by NVIDIA GPUs to solve your most complex problems, from scientific discovery to predictive maintenance, while minimizing costs.  

Solution Brief: Leverage HPC on AWS, powered by NVIDIA GPUs, to solve your most complex workload challenges 

High performance computing (HPC) continues to fuel advances in various industries, from healthcare and drug discovery, to energy with more efficient operations, to transporation with autonomous driving.

Whitepaper: Hyperion Research Opinion | Energy Efficiency is Driving Many HPC Users to the Cloud

The HPC market is witnessing a notable shift towards cloud adoption, partially driven by the benefits of enhanced energy efficiency. Organizations are increasingly recognizing that migrating HPC workloads to the cloud has the potential to lower operating costs for certain workload types.

Whitepaper: Hyperion Research Technology Spotlight | HPC and the Cloud - A Strong and Maturing Relationship

Cloud computing for high performance computing (HPC) has emerged as a strong solution to address some of the consistent issues HPC users are facing worldwide. Many of these issues have become driving forces behind cloud migration from on-premises solutions.

Infographic: The convergence of HPC and AI/ML

High performance computing (HPC) continues to develop at incredible pace, and the convergence of HPC and machine learning—and even quantum computing—is opening up new possibilities. Gain insights faster, and scale up your compute with AWS’ virtually unlimited compute capacity.

Infographic: The future of computational fluid dynamics

The need for faster, larger, more accurate design cycles, along with the performance and cost advantages of GPUs, are all driving the next generation of CFD applications forward. Download this infographic to learn how you can access the latest AWS technologies to accelerate your CFD simulations.

Infographic: Accelerate innovations in Healthcare and Life Sciences

 On AWS, researchers can access purpose-built HPC tools and services along with scientific and technical expertise to accelerate the pace of discovery. Learn how AWS customers are able to run workloads like molecular dynamics, medical imaging, modeling and simulations, and genomics with AWS HPC.

Infographic: Simplify deployment and management of HPC workloads

As the first cloud-based product to be verified as an Intel Select Solution, AWS ParallelCluster enables customers to easily deploy HPC workloads on AWS. Learn more about how to configure resources with a single parameter or by using pre-built templates. 

Whitepaper: HPC on AWS for Life Sciences

Read this whitepaper to learn about the purpose-built HPC services and tools you can use to field innovations in healthcare and life sciences. Learn about AWS’s extensive Partner Network and how AWS customers like AstraZeneca and Fred Hutchinson are lowering time-to-results, and running their workloads at scale on AWS.

eBook: Computer-Aided Engineering (CAE) on AWS Empowers Engineers to Innovate

In this eBook, learn how engineers can leverage the power and speed of high performance computing in the cloud to speed up standard CAE workflows and significantly reduce the cost and time required for each design iteration cycle.

Infographic: Five Reasons to Run Your CAE Workloads on AWS

Today, nearly all industries are using computer-aided engineering (CAE) in product development, including: automotive, aerospace, plant engineering, electronics, energy, and consumer goods. In this infographic, learn five reasons why AWS is a great choice to run your CAE workloads.

Whitepaper: The Cloud Steps up to Tightly Coupled HPC Codes

In this Technology Spotlight, Hyperion Research discusses how the cloud has evolved to support tightly coupled HPC codes.

Whitepaper: Lowering Time-to-Results with Elastic Fabric Adapter

Learn how you tightly coupled HPC or distributed ML codes can now scale to thousands of cores using Elastic Fabric Adapter, thereby providing you with results faster.

Analyst Spotlight: Computational Evaluation of Commercial Cloud HPC with a Global Atmospheric Model

This Hyperion Research paper discusses the US Naval Research Laboratory’s use of HPC and cloud capabilities for atmospheric modelling and forecasting. The paper highlights the performance gains and higher scalability obtained with the use of Amazon EC2 C5n instances and Elastic Fabric Adapter.

Whitepaper: Challenging Barriers to High Performance Computing in the Cloud

While adoption of cloud-based HPC solutions is increasing, misconceptions about their cost, security, and performance persist. It’s crucial to challenge these beliefs and break down common barriers to cloud-based HPC to prevent organizations large and small from being held back by outdated, inaccurate information. Learn how AWS can help you get started with HPC in the cloud quickly, securely, and cost-effectively.

Whitepaper: Democratizing High Performance Computing

Cloud-based HPC solutions are helping to break down barriers to entry for even the smallest teams that need access to high performance computing resources, and many different industries are finding it much easier to get started in HPC as a result.

Achieving optimal price/performance for your HPC workloads on AWS 

AWS customers benefit from a data center and network architecture that offers complete flexibility in catering for a variety of HPC workloads. Every use case has its unique needs and this guide helps determine the deal instance and configuration for running your HPC workloads on AWS.

Hyperion Research Technology Spotlight: Smart Orchestration Speeds HPC Workflows in the Cloud

This paper discusses the importance of cloud orchestration in the context of expanding HPC cloud usage and workflow heterogeneity. In this paper Amazon Web Service (AWS) llustrates how sophisticated cloud orchestration can lead to effieient HPC workflows in the cloud.

Whitepaper:  HPC on AWS Redefines What is Possible

From weather modeling to genome mapping to the search for extraterrestrial intelligence, HPC is helping to push the boundaries of what’s possible with advanced computing technologies. Once confined to government labs, large enterprises, and select academic organizations, today it is found across a wide range of industries.

Whitepaper:  What a TCO Analysis Won't Tell You

Organizations considering investments in high performance computing (HPC) should look deeply at the hidden costs of on-premises solutions. These factors, including lost productivity and missed innovation, can negatively affect other R&D investments that depend on HPC and thus lower revenues.

eBook: HPC on AWS -  Innovation Without Limits

AWS offers a highly customizable platform and robust partner community, allowing teams to collaborate from anywhere without the need for infrastructure upgrades. Reinvigorate enterprise collaboration previously held back by on-premises infrastructure with HPC on AWS.

Infographic:  Five Reasons to Run Your HPC Applications in the Cloud

High Performance Computing  has always been about solving the world's most complex problems. For too long, however, HPC applications and workloads have been constrained by limited on-premises infrastructure capacity, high capital expenditures, and the constant need for technology refreshes.

Whitepaper: Optimizing Electronic Design Automation (EDA) Workflows on AWS

Semiconductor and electronics companies using electronic design automation (EDA) can significantly accelerate their product development lifecycle and time to market by taking advantage of the near infinite compute , storage, and resources available on AWS. This whitepaper presents an overview of the EDA workflow, recommendations for moving EDA tools to AWS,  and the specific AWS architectural components to optimize EDA workloads on AWS.

Whitepaper: Cloud Computing for HPC Comes of Age

This Hyperion Research technology spotlight examines the dynamics of the fast-evolving Cloud HPC market and why AWS is well positioned to meet the needs of the HPC cloud computing market.

Whitepaper: Running HPC workloads on AWS

From genomics, computation chemistry to seismic modeling, learn how to run a variety of industry specific HPC workloads on AWS.

Reference architecture documents

Reference architecture : HPC Lens - Well Architected Framework


AWS HPC Blog channel
You can learn a lot from AWS HPC engineers by following the high performance computing (HPC) blog channel.

HPC Tech Shorts

You can learn a lot from AWS HPC engineers by subscribing to the high performance computing (HPC) Tech Short YouTube channel

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reInvent Sessions

AWS re:Invent 2023 - Confidently run your production HPC workloads on AWS (CMP213)
AWS re:Invent 2023 - HPC on AWS for semiconductors and healthcare life sciences (CMP214)
AWS re:Invent 2023 - Bridging research and computing to tackle the world's grand challenges (WPS207)
AWS re:Invent 2022 - HPC on AWS: Solve complex problems with pay-as-you-go infrastructure (CMP205)
AWS re:Invent 2022 – How AWS and aerospace and geospatial companies are rethinking HPC (CMP220)
AWS re:Invent 2022 - Redefining supercomputing on AWS (CMP222)
AWS re:Invent 2021 - HPC on AWS: Innovating without Infrastructure Constraints
AWS re:Invent 2021 – The future of HPC is looking a lot like ML
AWS re:Invent 2021 - Risk calculations using HPC and Spot Instances with Morgan Stanley
AWS re:Invent 2020 - HPC on AWS: Innovating without Infrastructure Constraints
AWS re:Invent 2020 – Blake Scholl of Boom on using AWS to enable commercial supersonic flight
AWS re:Invent 2019 - Monday Night Live with Peter DeSantis (1:29:55)
AWS re:Invent 2019: Powering global-scale predictive intelligence using HPC on AWS (47:21)
Remote desktop and application streaming with NICE DCV (29:44)
Using AWS ParallelCluster to simplify HPC cluster management (42:24)

Public data sets

When organizations make data open on AWS, scientists can access and analyze it, delivering innovative solutions to big challenges. AWS makes a variety of Public Data Sets available to researchers and the public, including:

  •       Landsat 8: All Landsat 8 scenes from 2015 and onward are made available each day, often within hours of production.
  •       NASA NEX: A collection of Earth science data sets maintained by NASA, including climate change projections and satellite images of the Earth's surface.
  •       NEXRAD on AWS: Real-time and archival data from the Next Generation Weather Radar (NEXRAD) network.
  •       1000 Genomes Project: This dataset contains the full genomic sequence of 1,700 individuals.
  •       The Cancer Genome Atlas (TCGA): Raw and processed genomic, transcriptomic, and epigenomic data from The Cancer Genome Atlas (TCGA) available to qualified researchers via the Cancer Genomics Cloud.
  •       The International Cancer Genome Consortium (ICGC): Whole genome sequence data available to qualified researchers via The International Cancer Genome Consortium (ICGC).

See a complete list of Public Datasets available in the AWS Cloud.


AWS Research Initiative

AWS helps researchers process complex workloads by providing the cost-effective, scalable and secure compute, storage, analytics, and artificial intelligence/machine learning capabilities needed to accelerate time-to-science. In addition to cutting edge technology services, AWS provides researchers with access to open data sets, funding resources, and the training critical to stand up their research and accelerate the pace of innovation globally.  Learn more >>


Peering with Global Research Networks

By peering with Global Research Networks, AWS gives researchers robust network connections to the AWS cloud. These network connections allow for reliable movement of data between your home institution, distributed data collection sites, and AWS.


AWS Cloud Credits for Research Program

The AWS Cloud Credits for Research Program supports researchers who seek to build cloud-hosted publicly available science-as-a-service applications and tools, perform proof of concept tests in the cloud, or train communities on the usage of the cloud for research workloads.

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AWS Global Data Egress Waiver Program

AWS makes cloud budgeting more predictable by waiving data egress fees in the AWS Cloud, for qualified researchers and academic customers. These are fees associated with “data transfer out from AWS to the Internet." Contact your AWS representative to learn more about this program

Learn more about AWS services for HPC

Learn about all the AWS services you can use to build an HPC solution on AWS.

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