Posted On: Oct 2, 2018

This Quick Start deploys Dynamic Read Analysis for GENomics Complete Suite (DRAGEN CS), a data analysis platform by Illumina, on the AWS Cloud in about 15 minutes.

DRAGEN CS enables ultra-rapid analysis of next-generation sequencing (NGS) data, significantly reduces the time required to analyze genomic data, and improves accuracy. It includes bioinformatics pipelines that provide highly optimized algorithms for mapping, aligning, sorting, duplicate marking, and haplotype variant calling. These pipelines include DRAGEN Germline V2, DRAGEN Somatic V2 (Tumor and Tumor/Normal), DRAGEN Virtual Long Read Detection (VLRD), DRAGEN RNA Gene Fusion, DRAGEN Joint Genotyping, and GATK Best Practices.

The Quick Start builds an AWS environment that spans two Availability Zones for high availability, and provisions two AWS Batch compute environments for Spot Instances and On-Demand Instances. These environments include DRAGEN F1 instances that are connected to field-programmable gate arrays (FPGAs) for hardware acceleration.

To get started:

You can also download the AWS CloudFormation templates that automate the deployment from GitHub.
To browse and launch other AWS Quick Start reference deployments, see our complete catalog.
Quick Starts are automated reference deployments that use AWS CloudFormation templates to deploy key technologies on AWS, following AWS best practices. This Quick Start was built by Illumina in collaboration with AWS solutions architects. Illumina is an AWS Advanced Technology Partner.