Open data
|
Deployed on AWS
The goal of the National Institutes of Health (NIH) Common Fund’s 4D Nucleome (4DN) program
is to study the three-dimensional organization of the nucleus in space and time (the 4th dimension).
The nucleus of a cell contains DNA, the genetic “blueprint” that encodes all of the genes a living
organism uses to produce proteins needed to carry out life-sustaining cellular functions. Understanding
the conformation of the nuclear DNA and how it is maintained or changes in response to environmental
and cellular cues over time will provide insights into basic biology as well as aspects of human
health and disease. The 4DN is an international consortium of researchers who generate data that
include results from a variety of genomics and imaging assays with a focus on, but not exclusive to,
those that demonstrate close contact between chromatin loci that are non-adjacent on the linear DNA
sequence of chromosomes. Additional assays probe the nuclear landscape in the context of interactions
o[...]
Overview
The goal of the National Institutes of Health (NIH) Common Fund’s 4D Nucleome (4DN) program is to study the three-dimensional organization of the nucleus in space and time (the 4th dimension). The nucleus of a cell contains DNA, the genetic “blueprint” that encodes all of the genes a living organism uses to produce proteins needed to carry out life-sustaining cellular functions. Understanding the conformation of the nuclear DNA and how it is maintained or changes in response to environmental and cellular cues over time will provide insights into basic biology as well as aspects of human health and disease. The 4DN is an international consortium of researchers who generate data that include results from a variety of genomics and imaging assays with a focus on, but not exclusive to, those that demonstrate close contact between chromatin loci that are non-adjacent on the linear DNA sequence of chromosomes. Additional assays probe the nuclear landscape in the context of interactions of chromatin with specific proteins, RNAs and epigenetic changes.
Features and programs
Open Data Sponsorship Program
This dataset is part of the Open Data Sponsorship Program, an AWS program that covers the cost of storage for publicly available high-value cloud-optimized datasets.
Pricing
This is a publicly available data set. No subscription is required.
Legal
Content disclaimer
Vendors are responsible for their product descriptions and other product content. AWS does not warrant that vendors' product descriptions or other product content are accurate, complete, reliable, current, or error-free.
Delivery details
AWS Data Exchange (ADX)
AWS Data Exchange is a service that helps AWS easily share and manage data entitlements from other organizations at scale.
Open data resources
Available with or without an AWS account.
- How to use
- To access these resources, reference the Amazon Resource Name (ARN) using the AWS Command Line Interface (CLI). Learn more
- Description
- Released and archived 4DNucleome data
- Resource type
- S3 bucket
- Amazon Resource Name (ARN)
- arn:aws:s3:::4dn-open-data-public
- AWS region
- us-east-1
- AWS CLI access (No AWS account required)
- aws s3 ls --no-sign-request s3://4dn-open-data-public/
Resources
Vendor resources
Support
Contact
Managed By
4DN Data Coordination and Integration Center (4DN-DCIC)
How to cite
4D Nucleome (4DN) was accessed on DATE from https://registry.opendata.aws/4dnucleome .
License
External data users may freely download, analyze, and publish results based on any 4DN data provided here without restrictions.
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