AWS HealthOmics pricing

As part of the AWS Free Tier, you can get started with AWS HealthOmics for free. Your Free Tier starts from the first month when you create your first AWS HealthOmics resource. The details of the AWS HealthOmics Free Tier are in the table below.

When you store genomic sequences in AWS HealthOmics storage, you pay for storage per gigabase per month. A gigabase is one billion bases from your imported sequence files (such as FASTQ, BAM, and CRAM). AWS HealthOmics storage stores the bases, quality scores, alignments, and other metadata from your source files. You pay per gigabase stored, so you don’t need to worry about optimal file formats or compression techniques. AWS HealthOmics takes care of all of that for you.

Sequence objects are called read sets and are logically equivalent to a FASTQ, BAM, or CRAM file. AWS HealthOmics storage offers you an active storage class and an archive storage class for your read sets. Read sets in the archive class cost less per month to store than read sets in the active class. Read sets in the active class can be accessed in milliseconds, while read sets in the archive tier need to be activated before they can be accessed. After read sets have not been accessed for 30 days, they automatically move to the lower-cost archive storage class until they are reactivated.

There is no import fee for read sets. AWS HealthOmics storage data is charged for a minimum storage duration of 30 days, and data deleted before 30 days incurs a prorated charge equal to the storage charge for the remaining days. AWS HealthOmics storage is designed for long-lived but infrequently accessed data that is retained for years.

There are two ways of accessing AWS HealthOmics storage data: Through read, write, and update through HealthOmics APIs and reading through S3 APIs.  For access through HealthOmics APIs,  You pay for GET requests made to your read-set objects. All other HealthOmics request types on read sets are free. For access through S3 APIs, COPY and LIST requests are billed separately from all other request types.  

GET and LIST requests through the Amazon S3 API usage will be billed at the S3 API rates (see pricing here).

AWS HealthOmics analytics helps you prepare your genomic variant data and genomic annotations for use with the broad suite of AWS analytics and machine learning services such as Amazon Athena and Amazon SageMaker. You can store any amount of genomic variant data, and you only pay for what you store. Data size is defined as the size of transformed data. However, when you query and analyze the data in other services, you pay for the use of those services.

AWS HealthOmics analytics data is charged for a minimum storage duration of 30 days, and data deleted before 30 days incurs a prorated charge equal to the storage charge for the remaining days.

AWS HealthOmics also manages the execution of bioinformatics workflows with private and Ready2Run workflows.

Private workflows enable you to bring your own bioinformatics scripts that are written in the most commonly used workflow languages. You can run private workflows with a single execution. You pay only for what you request and you are billed separately for omics instance types and run storage. All tasks in your workflow are mapped to the instance that is the best fit for their defined resources. For example, a task that is defined to use 8 CPUs and 60 GB of RAM will map to the omics.r.2xlarge instance type for execution.

Ready2Run workflows are pre-built workflows that have been packaged by industry third party software companies and open-source pipelines. You can simply use Ready2Run workflows to process your data with the most commonly used workflows like Germline and GATK-BP. Ready2Run workflows are pay-per-run which means you are charged the same price for every workflow.

For both private and Ready2Run workflows, logs are stored in Amazon CloudWatch logs in your account and billed in CloudWatch for as long as you choose to retain them. You can configure the service to report resource use per run for simplified budgeting, planning, and accounting.