Sold by: Florence Healthcare
Deployed on AWS
Florence eBinders digitizes and streamlines site workflows by managing eISFs, participant binders, and logs in a secure, compliant cloud platform. Enable remote monitoring, e-signatures, and team collaboration - all with built-in training for easy adoption.
4.5
Overview
Florence eBinders is a comprehensive electronic solution designed to digitize, automate, and integrate investigator site files, participant binders, and logs for research sites. This cloud-based platform enhances clinical research workflow by providing secure electronic management of study documents. It supports remote monitoring for sponsors and CROs, ensuring compliance with regulatory standards such as 21 CRF Part 11 and HIPAA. Florence eBinders allows research teams to electronically sign, manage, store, and collaborate on documents efficiently while offering complimentary training courses to facilitate seamless adoption.
Highlights
- Streamline eISFs, participant binders, and study logs in a secure, cloud-based platform.
- Enable remote access for sponsors/CROs and support compliant electronic signatures.
- Onboard research teams quickly with complimentary training and intuitive workflows.
Details
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Features and programs
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Pricing
Pricing is based on the duration and terms of your contract with the vendor, and additional usage. You pay upfront or in installments according to your contract terms with the vendor. This entitles you to a specified quantity of use for the contract duration. Usage-based pricing is in effect for overages or additional usage not covered in the contract. These charges are applied on top of the contract price. If you choose not to renew or replace your contract before the contract end date, access to your entitlements will expire.
Additional AWS infrastructure costs may apply. Use the AWS Pricing Calculator to estimate your infrastructure costs.
Dimension | Description | Cost/12 months |
|---|---|---|
Annual Commitment | Starter Pack | $30,000.00 |
Dimension | Description | Cost/unit |
|---|---|---|
Active Study Site | Customer's active Study-Site count for subscription fee per month | $0.01 |
Vendor refund policy
All fees are non-cancellable and non-refundable except as required by law.
Legal
Vendor terms and conditions
Upon subscribing to this product, you must acknowledge and agree to the terms and conditions outlined in the vendor's End User License Agreement (EULA) .
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Delivery details
Software as a Service (SaaS)
SaaS delivers cloud-based software applications directly to customers over the internet. You can access these applications through a subscription model. You will pay recurring monthly usage fees through your AWS bill, while AWS handles deployment and infrastructure management, ensuring scalability, reliability, and seamless integration with other AWS services.
Resources
Vendor resources
Support
Vendor support
For support inquiries, please reach out to our customer service at support@florencehc.com or visit our support page at
AWS infrastructure support
AWS Support is a one-on-one, fast-response support channel that is staffed 24x7x365 with experienced and technical support engineers. The service helps customers of all sizes and technical abilities to successfully utilize the products and features provided by Amazon Web Services.
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Customer reviews
Theresa P.
Centralized, Compliant, and Collaborative—A Game-Changer for Digital Regulatory Management
Reviewed on Nov 25, 2025
Review provided by G2
What do you like best about the product?
Centralized Digital Regulatory Binder
No more paper binders or scattered files—everything is in one secure, cloud-based location.
Easy access for monitors, auditors, and team members.
Remote Monitoring & Collaboration
Sponsors and CROs can review documents remotely, reducing the need for on-site visits.
Perfect for hybrid or decentralized trials.
Compliance & Audit Readiness
Built to meet FDA, ICH-GCP, and HIPAA standards.
Automatic version control and audit trails make inspections stress-free.
Real-Time Document Tracking
See who uploaded, signed, or reviewed documents instantly.
Reduces delays in study startup and ongoing compliance.
No more paper binders or scattered files—everything is in one secure, cloud-based location.
Easy access for monitors, auditors, and team members.
Remote Monitoring & Collaboration
Sponsors and CROs can review documents remotely, reducing the need for on-site visits.
Perfect for hybrid or decentralized trials.
Compliance & Audit Readiness
Built to meet FDA, ICH-GCP, and HIPAA standards.
Automatic version control and audit trails make inspections stress-free.
Real-Time Document Tracking
See who uploaded, signed, or reviewed documents instantly.
Reduces delays in study startup and ongoing compliance.
What do you dislike about the product?
Learning Curve
Initial setup and training can feel complex, especially for teams transitioning from paper binders.
Limited Customization
Some workflows and folder structures are rigid, making it hard to tailor to unique study needs.
Performance Issues
Uploading large files or navigating multiple studies can sometimes be slow.
Integration Challenges
While it integrates with eSign tools, connecting with other CTMS or EDC systems may require extra effort or support.
Initial setup and training can feel complex, especially for teams transitioning from paper binders.
Limited Customization
Some workflows and folder structures are rigid, making it hard to tailor to unique study needs.
Performance Issues
Uploading large files or navigating multiple studies can sometimes be slow.
Integration Challenges
While it integrates with eSign tools, connecting with other CTMS or EDC systems may require extra effort or support.
What problems is the product solving and how is that benefiting you?
Paper-Based Regulatory Binders
Traditional binders are hard to manage, prone to errors, and require physical storage.
Florence digitizes everything, eliminating paper and reducing clutter.
Slow Monitoring & Audits
On-site monitoring visits delay timelines and increase costs.
Florence enables remote monitoring, so sponsors and auditors can review documents anytime.
Compliance Risks
Manual tracking of signatures and version control can lead to non-compliance.
Florence provides automatic audit trails, version history, and secure eSignatures to meet FDA, ICH-GCP, and HIPAA standards.
Fragmented Communication
Emailing documents back and forth creates confusion and delays.
Florence centralizes communication and document sharing in one platform.
Faster Study Activation: Reduces time spent chasing documents and signatures.
Improved Compliance: Ensures your site is always inspection-ready.
Time Savings: Less manual filing and scanning means more time for participant care and coordination.
Remote Access: You can manage binders from anywhere, which is crucial for multi-site or decentralized trials.
Traditional binders are hard to manage, prone to errors, and require physical storage.
Florence digitizes everything, eliminating paper and reducing clutter.
Slow Monitoring & Audits
On-site monitoring visits delay timelines and increase costs.
Florence enables remote monitoring, so sponsors and auditors can review documents anytime.
Compliance Risks
Manual tracking of signatures and version control can lead to non-compliance.
Florence provides automatic audit trails, version history, and secure eSignatures to meet FDA, ICH-GCP, and HIPAA standards.
Fragmented Communication
Emailing documents back and forth creates confusion and delays.
Florence centralizes communication and document sharing in one platform.
Faster Study Activation: Reduces time spent chasing documents and signatures.
Improved Compliance: Ensures your site is always inspection-ready.
Time Savings: Less manual filing and scanning means more time for participant care and coordination.
Remote Access: You can manage binders from anywhere, which is crucial for multi-site or decentralized trials.
Kacie L.
Great product and service
Reviewed on Dec 03, 2024
Review provided by G2
What do you like best about the product?
Digital files are much easier to manage, and Florence is easier to use than any of the other software products we piloted. Since implementing, we have had excellent customer support and response to our feedback. Part 11 compliance is the number one reason we have been able to implement and continue to get support from our site. Monitors love it, and it allows for excellent quality control.
What do you dislike about the product?
Florence is very customizable, so it takes a lot of work for setup and to create our site templates. It is an ongoing process. It takes regular oversight and management, and that is time and resources spent by our site.
What problems is the product solving and how is that benefiting you?
Part 11 compliance for personal records, digital records, digital signature collection, digital file storage, remote access, remote monitoring, and full audit trail access
Hospital & Health Care
Florence eBinders
Reviewed on Aug 27, 2024
Review provided by G2
What do you like best about the product?
I love how easy it is to have every study you work on at your fingertips.
What do you dislike about the product?
I don't like that you couldn't add a sigature field for PI's to sign
What problems is the product solving and how is that benefiting you?
Its has eased the use of paper binders.
Hospital & Health Care
Great company that has a user friendly product and great to work with.
Reviewed on Nov 16, 2023
Review provided by G2
What do you like best about the product?
Easy to organize and navigate as a user and an auditor.
What do you dislike about the product?
There is nothing I dislike about Florence eBinders
What problems is the product solving and how is that benefiting you?
Efficiency and better organization and access to our files
Hospital & Health Care
Efficient and flexible
Reviewed on Nov 16, 2023
Review provided by G2
What do you like best about the product?
The system is flexible and functional. The company listens and is earnest and honest in its communication.
What do you dislike about the product?
It is still being refined in some ways so improvement is still necessary.
What problems is the product solving and how is that benefiting you?
Providing a e-signature solution and folder structure controls for document access and management.