Open data
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Deployed on AWS
The Cancer Genome Atlas (TCGA), a collaboration between the National Cancer Institute (NCI) and National Human Genome Research Institute (NHGRI), aims to generate comprehensive, multi-dimensional maps of the key genomic changes in major types and subtypes of cancer. TCGA has analyzed matched tumor and normal tissues from 11,000 patients, allowing for the comprehensive characterization of 33 cancer types and subtypes, including 10 rare cancers.
The dataset contains open Clinical Supplement, Biospecimen Supplement, RNA-Seq Gene Expression Quantification, miRNA-Seq Isoform Expression Quantification, miRNA Expression Quantification, Genotyping Array Copy Number Segment, Genotyping Array Masked Copy Number Segment, Genotyping Array Gene Level Copy Number Scores, and WXS Masked Somatic Mutation data from Genomic Data Commons (GDC).
This dataset also contains controlled Whole Exome Sequencing (WXS), RNA-Seq, miRNA-Seq, ATAC-Seq Aligned Reads, WXS Annotated Somatic Mutation, WXS Raw Somat[...]
Overview
The Cancer Genome Atlas (TCGA), a collaboration between the National Cancer Institute (NCI) and National Human Genome Research Institute (NHGRI), aims to generate comprehensive, multi-dimensional maps of the key genomic changes in major types and subtypes of cancer. TCGA has analyzed matched tumor and normal tissues from 11,000 patients, allowing for the comprehensive characterization of 33 cancer types and subtypes, including 10 rare cancers. The dataset contains open Clinical Supplement, Biospecimen Supplement, RNA-Seq Gene Expression Quantification, miRNA-Seq Isoform Expression Quantification, miRNA Expression Quantification, Genotyping Array Copy Number Segment, Genotyping Array Masked Copy Number Segment, Genotyping Array Gene Level Copy Number Scores, and WXS Masked Somatic Mutation data from Genomic Data Commons (GDC). This dataset also contains controlled Whole Exome Sequencing (WXS), RNA-Seq, miRNA-Seq, ATAC-Seq Aligned Reads, WXS Annotated Somatic Mutation, WXS Raw Somatic Mutation, and WXS Aggregated Somatic Mutation data from GDC. TCGA is made available on AWS via the NIH STRIDES Initiative .
Features and programs
Open Data Sponsorship Program
This dataset is part of the Open Data Sponsorship Program, an AWS program that covers the cost of storage for publicly available high-value cloud-optimized datasets.
Pricing
This is a publicly available data set. No subscription is required.
Legal
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Delivery details
AWS Data Exchange (ADX)
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Open data resources
Available with or without an AWS account.
- How to use
- To access these resources, reference the Amazon Resource Name (ARN) using the AWS Command Line Interface (CLI). Learn more
- Description
- Clinical Supplement, Biospecimen Supplement, RNA-Seq Gene Expression Quantification, miRNA-Seq Isoform Expression Quantification, miRNA Expression Quantification, Genotyping Array Copy Number Segment, Genotyping Array Masked Copy Number Segment, Genotyping Array Gene Level Copy Number Scores, WXS Masked Somatic Mutation
- Resource type
- S3 bucket
- Amazon Resource Name (ARN)
- arn:aws:s3:::tcga-2-open
- AWS region
- us-east-1
- AWS CLI access (No AWS account required)
- aws s3 ls --no-sign-request s3://tcga-2-open/
- Description
- WXS/RNA-Seq/miRNA-Seq/ATAC-Seq Aligned Reads, WXS Annotated Somatic Mutation, WXS Raw Somatic Mutation, WXS Aggregated Somatic Mutation
- Resource type
- S3 bucket
- Amazon Resource Name (ARN)
- arn:aws:s3:::tcga-2-controlled
- AWS region
- us-east-1
- AWS CLI access (No AWS account required)
- aws s3 ls --no-sign-request s3://tcga-2-controlled/
Resources
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How to cite
The Cancer Genome Atlas was accessed on DATE from https://registry.opendata.aws/tcga .
License
NIH Genomic Data Sharing Policy: https://gdc.cancer.gov/access-data/data-access-policies