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    KlastroHeron BioMedical, Biomedical Literature & EMA Regulatory Search

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    Deployed on AWS
    KlastroHeron BioMedical is an MCP server that searches Europe PMC and the EMA regulatory database, then returns one synthesized, cited answer, not a raw list of papers, and not a diagnostic tool. It runs entirely inside your own AWS account via Amazon Bedrock, with no seller-hosted backend and no customer data collection.

    Overview

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    KlastroHeron BioMedical is a Model Context Protocol (MCP) server for biomedical literature search and regulatory lookup. Given a natural-language question, it searches Europe PMC for relevant research papers and, for named-drug questions, cross-checks the European Medicines Agency's (EMA) public regulatory database, including marketing authorisation status, ATC code, orphan/biosimilar/generic flags, and any safety alerts on record. It returns a single synthesized, cited answer rather than a raw search result list, so downstream agents and applications get a usable answer, not a research task.

    EMA data is downloaded directly from EMA's own public exports and refreshed automatically (at startup, then monthly), so there is no manual data-update process. Premium and Enterprise plans additionally receive citation-metric enrichment and an extracted methodology summary alongside each answer. The service auto-detects the language of each question and answers in kind, across 31 supported languages configurable per deployment.

    The product is delivered as a single self-hosted container exposing two MCP tools, search_literature and lookup_drug_regulatory_info, over stateless streamable-HTTP, so it can be called directly by any MCP-compatible orchestrator or agent platform. It runs entirely inside your own AWS account: LLM inference goes through Amazon Bedrock using your account's IAM role, no data is sent to or stored by the seller, and there is no seller-operated backend. This is a research and regulatory-information tool, not a medical device, and it is not intended for diagnosis or treatment decisions.

    Highlights

    • Cited Literature Search & Synthesis: Searches Europe PMC and returns one synthesized, cited answer, not a raw paper list, with citation-metric badges and methodology summaries on Premium/Enterprise plans.
    • EMA Regulatory Database Integration: For named-drug questions, cross-checks EMA's public regulatory data (authorisation status, ATC code, safety alerts), refreshed automatically from EMA's own exports with no manual updates required.
    • Self-Hosted, Multi-Language MCP Server: Deploys as a standard MCP-compliant container in your own AWS account via Amazon Bedrock, with no seller-hosted backend, no data leaving your environment, and auto-detected support across 31 languages.

    Details

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    Delivery option
    KlastroHeron BioMedical MCP Server

    Latest version

    Operating system
    Linux

    Deployed on AWS
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    Pricing

    KlastroHeron BioMedical, Biomedical Literature & EMA Regulatory Search

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    Pricing is based on the duration and terms of your contract with the vendor. This entitles you to a specified quantity of use for the contract duration. If you choose not to renew or replace your contract before it ends, access to these entitlements will expire.
    Additional AWS infrastructure costs may apply. Use the AWS Pricing Calculator  to estimate your infrastructure costs.

    1-month contract (3)

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    Dimension
    Description
    Cost/month
    Academic & Personal License
    License for a single individual (physician or independent researcher) or for staff at one academic or non-profit research institution.
    $149.00
    Commercial Team License
    License for one research or clinical team at a commercial biotech, pharmaceutical, or CRO organization.
    $1,490.00
    Enterprise License
    License for deployment across all teams and sites within one commercial organization.
    $6,490.00

    AI Insights

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    Dimensions summary

    You choose a license based on who will use the product and how widely you deploy it. All three dimensions bill per unit under a contract. The Academic & Personal License covers one individual or the staff at a single academic or non-profit institution. The Commercial Team License covers one research or clinical team at a commercial biotech, pharmaceutical, or CRO organization. The Enterprise License extends coverage across all teams and sites within one commercial organization. Pricing scales by user scope, moving from individual and institutional use, to a single commercial team, to an entire commercial organization.

    Top-of-mind questions for buyers

    Pick the license that matches your user scope. The Academic & Personal License covers one individual or the staff at a single academic or non-profit institution. The Commercial Team License covers one research or clinical team at a commercial organization. The Enterprise License covers all teams and sites within one commercial organization. Each unit is one license at that scope.
    The Commercial Team License covers a single research or clinical team. If usage spreads to more teams or sites within one commercial organization, the Enterprise License covers all teams and sites. Moving from one scope to another means changing your license selection, not adding partial units to the same team license.
    Each license gives access to a biomedical evidence engine that searches biomedical literature and European regulatory data. The engine runs in your environment, with models called through Amazon Bedrock. The licenses differ only by who may use it and how widely you deploy it, not by the underlying search capability.
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    Vendor refund policy

    Refunds are evaluated case-by-case. Customers may request a refund within 14 days of purchase if the software has not been deployed to production. Contract-based licenses (Academic & Personal License, Commercial Team License, Enterprise License) are non-refundable once deployed to production or after 30 days from the contract start date, except as required by law. To request a refund, contact support@klastrovanie.com  with your AWS account ID and order details. We respond within 3 business days.

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    Usage information

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    Delivery details

    KlastroHeron BioMedical MCP Server

    Supported services: Learn more 
    • Amazon ECS
    • Amazon EKS
    Container image

    Containers are lightweight, portable execution environments that wrap server application software in a filesystem that includes everything it needs to run. Container applications run on supported container runtimes and orchestration services, such as Amazon Elastic Container Service (Amazon ECS) or Amazon Elastic Kubernetes Service (Amazon EKS). Both eliminate the need for you to install and operate your own container orchestration software by managing and scheduling containers on a scalable cluster of virtual machines.

    Version release notes

    Minor bug fixed version.

    A stateless MCP server for biomedical literature search (Europe PMC) and EMA regulatory lookup, powered by Amazon Bedrock. Two tools: search_literature (synthesized, cited answers) and lookup_drug_regulatory_info (direct EMA authorisation/safety lookup). Supports 7 default languages, configurable via kh-config.yml, with automatic monthly EMA data refresh. Responses include a structured "sections" field for building tabbed UIs, in addition to the flat synthesized answer.

    Additional details

    Usage instructions

    Container listens on port 8000, path /mcp (MCP streamable-HTTP transport, stateless, no session state, no web UI).

    Required environment variables:

    • KH_LLM_PROVIDER=bedrock
    • AWS_REGION=<your AWS region, e.g. eu-north-1>
    • KH_BEDROCK_GEO=<eu|us|au|jp|global> (must match your AWS_REGION's geography)

    Optional environment variables:

    • KH_EMA_ENABLED=true (default, enables EMA regulatory lookup; EMA data is downloaded automatically at container startup and refreshed monthly)
    • KH_LANGUAGES=en,ko,ja (comma-separated, restricts which languages are loaded; defaults to a standard set if omitted)

    License entitlement (required IAM permissions): This product validates its AWS Marketplace contract entitlement via AWS License Manager. No license keys or extra configuration are required - the container reads its entitlement automatically using the task/pod execution role. Grant that role the following permissions, or the service will stop responding after a short grace period:

    • license-manager:CheckoutLicense
    • license-manager:ExtendLicenseConsumption
    • license-manager:CheckInLicense
    • license-manager:ListReceivedLicenses On first use of AWS License Manager in the account, create the service-linked role once: aws iam create-service-linked-role --aws-service-name license-manager.amazonaws.com If the contract lapses, /mcp returns HTTP 402 and /health returns HTTP 503; renewing the contract restores service automatically, with no redeploy.

    Health check: GET /health on port 8000 returns {"status":"ok", ...} with HTTP 200 while entitled, and HTTP 503 if the AWS Marketplace entitlement is not active. This image does not include curl. For an ECS container-level health check, use: "healthCheck": {"command": ["CMD-SHELL", "python3 -c "import urllib.request; urllib.request.urlopen('http://localhost:8000/health ', timeout=3)" || exit 1"], "interval": 30, "timeout": 5, "retries": 3} For EKS, a standard httpGet livenessProbe/readinessProbe against path /health, port 8000 works with no changes, since Kubernetes probes are performed by the kubelet rather than from inside the container, so no curl is required.

    Full API reference, response schema, and language configuration are in the User Manual under Resources.

    Resources

    Vendor resources

    Support

    Vendor support

    Technical support is available for KlastroHeron BioMedical deployment, configuration, container operation, and MCP integration with agent platforms and orchestrators. Support includes assistance with installation issues, container configuration, Amazon Bedrock setup, language configuration, and product-related technical questions.

    Standard support is provided by email on business days. Enterprise customers and customers purchasing through a Private Offer may receive additional deployment and integration support according to the terms of their agreement.

    Support email: support@klastrovanie.com 

    AWS infrastructure support

    AWS Support is a one-on-one, fast-response support channel that is staffed 24x7x365 with experienced and technical support engineers. The service helps customers of all sizes and technical abilities to successfully utilize the products and features provided by Amazon Web Services.

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