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    Cohort Equivalency for Clinical Trials

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    Deployed on AWS
    Simply and quickly demonstrate efficacy, safety, and superiority for drug label extensions, novel therapeutics, and generics

    Overview

    Our Platform leverages core competencies in processing high dimensional data sets, Causal Inference, Bayesian and Machine Learning  for the specific needs of Pharma and Healthcare by addressing specific top of mind use cases. These are built on a foundation of establishing Cohort Equivalency that brings the rigor of traditional randomized clinical trials to RWD. More specifically, we address limitations of Propensity Scoring when it comes to High Dimension Data.

    Highlights

    • The Pattern Sciences’ Platform super charges pharmaceutical development by providing pre-built playbooks and optimizations for specific use cases. Use Cases include: - Synthetic Control Arms for Clinical Trials - Comparative Drug Analysis to meet the threat of Generics (Two Arms Synthetic) - Showing drug efficacy over others pre or post FDA approvals (Two+ Arms) - Intervention Analysis for Value Based Care - Off Label Effectiveness Analysis  - Population Equivalency  - Label Expansions - Identify and validate novel drug or biomarkers for future therapeutics

    Details

    Delivery method

    Latest version

    Deployed on AWS

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    Pricing

    Cohort Equivalency for Clinical Trials

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    Pricing is based on actual usage, with charges varying according to how much you consume. Subscriptions have no end date and may be canceled any time.
    Additional AWS infrastructure costs may apply. Use the AWS Pricing Calculator  to estimate your infrastructure costs.

    Usage costs (32)

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    Dimension
    Description
    Cost/host/hour
    ml.t2.medium Inference (Real-Time)
    Recommended
    Model inference on the ml.t2.medium instance type, real-time mode
    $0.00
    ml.m5.large Inference (Batch)
    Recommended
    Model inference on the ml.m5.large instance type, batch mode
    $0.00
    ml.m4.4xlarge Inference (Real-Time)
    Model inference on the ml.m4.4xlarge instance type, real-time mode
    $0.00
    ml.t2.xlarge Inference (Real-Time)
    Model inference on the ml.t2.xlarge instance type, real-time mode
    $0.00
    ml.m4.10xlarge Inference (Real-Time)
    Model inference on the ml.m4.10xlarge instance type, real-time mode
    $0.00
    ml.t2.large Inference (Real-Time)
    Model inference on the ml.t2.large instance type, real-time mode
    $0.00
    ml.t2.2xlarge Inference (Real-Time)
    Model inference on the ml.t2.2xlarge instance type, real-time mode
    $0.00
    ml.m4.4xlarge Inference (Batch)
    Model inference on the ml.m4.4xlarge instance type, batch mode
    $0.00
    ml.m5.4xlarge Inference (Batch)
    Model inference on the ml.m5.4xlarge instance type, batch mode
    $0.00
    ml.m4.16xlarge Inference (Batch)
    Model inference on the ml.m4.16xlarge instance type, batch mode
    $0.00

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    This product is offered for free. If there are any questions, please contact us for further clarifications.

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    Usage information

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    Delivery details

    Amazon SageMaker model

    An Amazon SageMaker model package is a pre-trained machine learning model ready to use without additional training. Use the model package to create a model on Amazon SageMaker for real-time inference or batch processing. Amazon SageMaker is a fully managed platform for building, training, and deploying machine learning models at scale.

    Deploy the model on Amazon SageMaker AI using the following options:
    Deploy the model as an API endpoint for your applications. When you send data to the endpoint, SageMaker processes it and returns results by API response. The endpoint runs continuously until you delete it. You're billed for software and SageMaker infrastructure costs while the endpoint runs. AWS Marketplace models don't support Amazon SageMaker Asynchronous Inference. For more information, see Deploy models for real-time inference  .
    Deploy the model to process batches of data stored in Amazon Simple Storage Service (Amazon S3). SageMaker runs the job, processes your data, and returns results to Amazon S3. When complete, SageMaker stops the model. You're billed for software and SageMaker infrastructure costs only during the batch job. Duration depends on your model, instance type, and dataset size. AWS Marketplace models don't support Amazon SageMaker Asynchronous Inference. For more information, see Batch transform for inference with Amazon SageMaker AI  .
    Version release notes

    Initial Version

    Additional details

    Inputs

    Summary

    The input for the Cohort Equivalence package is of application/json. The json has two objects an X and y. The X is a dataset which used to predict whether the two population cohorts are equivalent, the y denotes the cohort either 1 or a 0.

    The type of X is a list of lists of double. The y is a list of population group of either 1 or 0 denoting which group it belongs to

    Limitations for input type
    For input data, the X inner list should be a length of 12.
    https://bitbucket.org/nathesh92/cohort_equivalency/src/master/test_data.json
    https://bitbucket.org/nathesh92/cohort_equivalency/src/master/test_data.json

    Input data descriptions

    The following table describes supported input data fields for real-time inference and batch transform.

    Field name
    Description
    Constraints
    Required
    X
    This a list of length k, where each element of the list is a list of length 12. The list of length 12 are the features corresponding to the cohort population.
    Type: Continuous Minimum: -99 Maximum: 99
    Yes
    y
    This is a list of length k, where each element of the list corresponds to cohort group. The valid values for this are either 0 or 1.
    Type: Integer Minimum: 0 Maximum: 1
    Yes

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