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    CIViC (Clinical Interpretation of Variants in Cancer)

     Info
    Open data
    |
    Deployed on AWS
    Precision medicine refers to the use of prevention and treatment strategies that are tailored to the unique features of each individual and their disease. In the context of cancer this might involve the identification of specific mutations shown to predict response to a targeted therapy. The biomedical literature describing these associations is large and growing rapidly. Currently these interpretations exist largely in private or encumbered databases resulting in extensive repetition of effort. Realizing precision medicine will require this information to be centralized, debated and interpreted for application in the clinic. CIViC is an open access, open source, community-driven web resource for Clinical Interpretation of Variants in Cancer. Our goal is to enable precision medicine by providing an educational forum for dissemination of knowledge and active discussion of the clinical significance of cancer genome alterations.

    Overview

    Precision medicine refers to the use of prevention and treatment strategies that are tailored to the unique features of each individual and their disease. In the context of cancer this might involve the identification of specific mutations shown to predict response to a targeted therapy. The biomedical literature describing these associations is large and growing rapidly. Currently these interpretations exist largely in private or encumbered databases resulting in extensive repetition of effort. Realizing precision medicine will require this information to be centralized, debated and interpreted for application in the clinic. CIViC is an open access, open source, community-driven web resource for Clinical Interpretation of Variants in Cancer. Our goal is to enable precision medicine by providing an educational forum for dissemination of knowledge and active discussion of the clinical significance of cancer genome alterations.

    Features and programs

    Open Data Sponsorship Program

    This dataset is part of the Open Data Sponsorship Program, an AWS program that covers the cost of storage for publicly available high-value cloud-optimized datasets.

    Pricing

    This is a publicly available data set. No subscription is required.

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    Legal

    Content disclaimer

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    Usage information

     Info

    Delivery details

    AWS Data Exchange (ADX)

    AWS Data Exchange is a service that helps AWS easily share and manage data entitlements from other organizations at scale.

    Open data resources

    Available with or without an AWS account.

    How to use
    To access these resources, reference the Amazon Resource Name (ARN) using the AWS Command Line Interface (CLI). Learn more 
    Description
    Monthly CIViC data dumps including feature, variant, assertion, and evidence tables.
    Resource type
    S3 bucket
    Amazon Resource Name (ARN)
    arn:aws:s3:::civic-aws-opendata
    AWS region
    us-west-2
    AWS CLI access (No AWS account required)
    aws s3 ls --no-sign-request s3://civic-aws-opendata/
    Description
    Notifications for monthly CIViC data availability.
    Resource type
    SNS topic
    Amazon Resource Name (ARN)
    arn:aws:sns:us-west-2:182652044697:civic-aws-opendata-object_created
    AWS region
    us-west-2

    Resources

    Support

    Managed By

    The Griffith Lab at Washington University School of Medicine

    How to cite

    CIViC (Clinical Interpretation of Variants in Cancer) was accessed on DATE from https://registry.opendata.aws/civic .

    License

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