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Deployed on AWS
MedGemma 1.5 4B is Google's open-weight multimodal medical AI model, fine-tuned for radiology, pathology, ophthalmology, dermatology, and clinical reasoning. Deploy as a managed SageMaker real-time endpoint in minutes.
Overview
Overview
Tech 42 packages Google's MedGemma 1.5 4B as a production-ready Amazon SageMaker Model Package so your team can deploy a state-of-the-art medical AI backend in minutes - no infrastructure setup, no model serving complexity. MedGemma 1.5 4B is the latest generation of Google's open-weight multimodal models built specifically for healthcare AI applications.
What MedGemma 1.5 4B Can Do
- Interpret CT and MRI scans in 3D
- Analyze whole-slide histopathology images
- Compare longitudinal chest X-rays against prior images
- Extract structured data from medical lab reports
- Interpret EHR text using FHIR-compatible records
- Answer medical questions across radiology, dermatology, ophthalmology, and pathology
Deployment
Deploy with one click. The endpoint exposes an OpenAI-compatible REST API (/v1/chat/completions) - a drop-in replacement for existing OpenAI API clients. Compatible with the SageMaker Python SDK and AWS SDK (Boto3). No GPU orchestration or container management required.
Validated on Real-World Medical Data
Tested against established medical datasets covering imaging, clinical reasoning, and document understanding. View full benchmark results on Hugging Face .
- Imaging - MIMIC-CXR, CheXpert, CXR14, CT-RATE, MS-CXR-T, PathMCQA, WSI-Path, PAD-UFES-20, SCIN, ISIC, EyePACS, SLAKE, VQA-RAD, Chest ImaGenome, MedXpertQA
- Text Reasoning - MedQA, MedMCQA, PubMedQA, MMLU Med, MedXpertQA, AfriMed-QA
- Medical Records - EHRNoteQA, EHRQA
- Document Understanding - Mendeley Clinical Lab Reports
SageMaker Real-Time Benchmark Results
Benchmarks run on G6e and G7e endpoints under streaming load, scaling concurrency from c1 to c64. G7e delivers substantially stronger performance.
| Instance | c8 avg RPS | c8 p90 RPS | c8 p90 TTFT | c8 p90 full response |
|---|---|---|---|---|
| G6e | 0.47 RPS | 0.58 RPS | 15.02s | 17.93s |
| G7e | 2.55 RPS | 2.74 RPS | 1.41s | 3.15s |
Highlights
- Google's Medical Multimodal AI - Private, In Your AWS Account: Deploy MedGemma 1.5 4B as a managed SageMaker endpoint. Radiology, pathology, EHR, and lab report understanding - no PHI leaves your VPC.
- OpenAI-Compatible API via vLLM - Zero SDK Changes for Your App: Served by vLLM with a native /v1/chat/completions endpoint. Integrate using the OpenAI Python SDK, LangChain, or any HTTP client - no custom wrappers needed.
- Deploy in minutes: Zero infrastructure management
Details
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Pricing
Pricing is based on actual usage, with charges varying according to how much you consume. Subscriptions have no end date and may be canceled any time.
Additional AWS infrastructure costs may apply. Use the AWS Pricing Calculator to estimate your infrastructure costs.
Dimension | Description | Cost/host/hour |
|---|---|---|
ml.g5.2xlarge Inference (Batch) Recommended | Model inference on the ml.g5.2xlarge instance type, batch mode | $1.50 |
ml.g7e.2xlarge Inference (Real-Time) Recommended | Model inference on the ml.g7e.2xlarge instance type, real-time mode | $1.50 |
ml.g5.xlarge Inference (Batch) | Model inference on the ml.g5.xlarge instance type, batch mode | $1.50 |
ml.g5.4xlarge Inference (Batch) | Model inference on the ml.g5.4xlarge instance type, batch mode | $1.50 |
ml.g6e.2xlarge Inference (Real-Time) | Model inference on the ml.g6e.2xlarge instance type, real-time mode | $1.50 |
ml.g6e.4xlarge Inference (Real-Time) | Model inference on the ml.g6e.4xlarge instance type, real-time mode | $1.50 |
ml.g7e.4xlarge Inference (Real-Time) | Model inference on the ml.g7e.4xlarge instance type, real-time mode | $1.50 |
Dimensions summary
You pay by the host-hour for the instance you run, so cost scales with runtime and instance size. Dimensions split into two inference modes. Batch mode runs offline jobs over a dataset and covers three ml.g5 sizes: xlarge, 2xlarge, and 4xlarge. Real-time mode runs a persistent endpoint for low-latency requests and covers the ml.g6e 2xlarge and 4xlarge plus the ml.g7e 2xlarge and 4xlarge. Within each family, larger sizes carry more compute. Charges accrue while an endpoint or job runs, and stop only when you delete those resources.
Top-of-mind questions for buyers
One host-hour is one instance running for one hour. Batch mode uses the ml.g5 xlarge, 2xlarge, or 4xlarge sizes. Real-time mode uses the ml.g6e or ml.g7e 2xlarge and 4xlarge sizes. Larger sizes carry more compute per hour. You are billed per running hour for each instance.
Charges accrue while a real-time endpoint stays InService or a batch job stays InProgress, even when idle. You stop charges only by deleting the endpoint or stopping the job. Canceling the Marketplace subscription alone does not stop these charges.
Both meter host-hours per instance. Batch mode runs an offline job over a dataset in S3, then finishes and stops charging. Real-time mode keeps a persistent endpoint running for low-latency requests, so it bills continuously until you delete it. Batch suits bulk processing; real-time suits interactive use.
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Delivery details
Amazon SageMaker model
An Amazon SageMaker model package is a pre-trained machine learning model ready to use without additional training. Use the model package to create a model on Amazon SageMaker for real-time inference or batch processing. Amazon SageMaker is a fully managed platform for building, training, and deploying machine learning models at scale.
Deploy the model on Amazon SageMaker AI using the following options:
Version release notes
Initial release of MedGemma 1.5 4B on AWS Marketplace. This version includes the multimodal 4B parameter model supporting medical text reasoning and image comprehension across CT, MRI, chest X-ray, dermatology, and whole-slide histopathology modalities. Built on Gemma 3 architecture with improved accuracy on medical text benchmarks over MedGemma 1.
Additional details
Inputs
- Summary
Accepts JSON payloads via the /invocations endpoint. Supports two modes: (1) text-only, providing a prompt string under the "inputs" key; (2) multimodal, providing a messages array with interleaved text and base64-encoded image content following the Gemma chat template format. Supported image types: JPEG, PNG. Maximum image size: 1024×1024 pixels. Content-Type must be application/json.
- Limitations for input type
- Maximum prompt length: 8,192 tokens. Images must be base64-encoded and embedded inline; external image URLs are not supported (no network access at inference time). Supported content types: application/json only. Batch transform inputs must use JSON Lines format (.jsonl), one JSON object per line.
- Input MIME type
- application/json
{
"inputs": {
"messages": [
{
"role": "user",
"content": [
{
"type": "image",
"image": "data:image/jpeg;base64,<BASE64_ENCODED_IMAGE>"
},
{
"type": "text",
"text": "Describe the findings in this chest X-ray and identify any abnormalities."
}
]
}
]
},
"parameters": {
"max_new_tokens": 512,
"temperature": 0.3
}
}
{"inputs": {"messages": [{"role": "user", "content": [{"type": "image", "image": "data:image/jpeg;base64,<BASE64_IMAGE_1>"}, {"type": "text", "text": "Describe the findings in this chest X-ray."}]}]}, "parameters": {"max_new_tokens": 512, "temperature": 0.3}}
{"inputs": {"messages": [{"role": "user", "content": [{"type": "image", "image": "data:image/jpeg;base64,<BASE64_IMAGE_2>"}, {"type": "text", "text": "Identify any abnormalities visible in this MRI scan."}]}]}, "parameters": {"max_new_tokens": 512, "temperature": 0.3}}
{"inputs": {"messages": [{"role": "user", "content": [{"type": "image", "image": "data:image/png;base64,<BASE64_IMAGE_3>"}, {"type": "text", "text": "What dermatological condition does this image suggest?"}]}]}, "parameters": {"max_new_tokens": 512, "temperature": 0.3}}
Input data descriptions
The following table describes supported input data fields for real-time inference and batch transform.
Field name | Description | Constraints | Required |
|---|---|---|---|
inputs | Text prompt string, or a messages array for multimodal inputs | Max 8,192 tokens | Yes |
max_new_tokens | Maximum number of tokens to generate in the response | 1–2048. Default: 512 | No |
temperature | Controls randomness. Lower values produce more deterministic output | 0.0–1.0. Default: 0.3 | No |
top_p | Nucleus sampling probability threshold | 0.0–1.0. Default: 0.9 | No |
top_k | Limits vocabulary to the top-k most likely tokens at each step | 1–100. Default: 50 | No |
return_full_text | If true, the input prompt is prepended to the generated output | Default: false | No |
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Support
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Contact us at support@tech42consulting.com or visit our website at tech42consulting.com
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