Chiral by N-21 AI is a clinical-grade agentic AI platform for Medicare Advantage and Dual-Eligible risk adjustment. It improves coding accuracy, reduces RADV exposure, and protects RAF revenue through a closed-loop, human-governed workflow spanning the entire HCC lifecycle, from suspecting and coding to evidence validation and RADV audit support. Every diagnosis is linked to explainable, audit-ready clinical evidence, enabling accurate, defensible RAF capture. HIPAA-compliant, SOC 2 Type II, and deployable securely within your AWS environment.
Chiral is an agentic AI platform purpose-built for risk adjustment in CMS-capitated senior healthcare, with an initial focus on Medicare Advantage and Dual-Eligible populations.
Rather than surfacing insights alone, Chiral drives execution across the full risk adjustment lifecycle, including patient, encounter, documentation, coding, RAF, payment, audit, and feedback, operating as a single, real-time system of record for CMS outcomes.
Built on a human-in-the-lead model, Chiral's in-production agents handle suspecting, HCC extraction, chart retrieval, and RADV audit support, while linking every submitted code to its supporting clinical evidence for a transparent, explainable, audit-ready trail.
Your coding and analytics teams stay in control of clinical judgment. Routine retrieval, MEAT validation, and evidence assembly run continuously in the background, improving consistency and capture with every review cycle.
The platform ingests structured and unstructured data across claims, clinical records, labs, encounters, and pharmacy through an interoperability layer, and embeds directly into existing payer and provider workflows.
Chiral extends beyond core risk adjustment into managed outcomes and value-based care, including quality and Star Ratings support, care coordination and transitions-of-care automation, utilization and case management, and population health.
Defend every diagnosis: Audit-ready evidence packs and immutable, explainable trails engineered to withstand CMS RADV scrutiny and extrapolation.
Prevent clawback exposure: Flag unsupported HCCs and documentation gaps before submission, not after an audit notice.
Keep humans in the lead: Coders and compliance staff review, override, and approve while the AI handles exhaustive retrieval and validation.
Capture accurate, consistent RAF: In-production agents embed into existing workflows for prospective and retrospective review at scale.
Secure by attestation and sovereign: HIPAA-compliant, SOC 2 Type II, and supported by a signed BAA. Deployed inside your AWS environment so no PHI leaves your control.
Operated by N-21 AI, Chiral gives Medicare Advantage plans, Duals programs, and risk-bearing providers a single, real-time system of record for defensible CMS outcomes.
Highlights
Audit-defensible RAF, end to end: Chiral drives the full risk adjustment lifecycle, including suspecting, HCC extraction, coding, and RADV audit support, and links every submitted diagnosis to its supporting clinical evidence for a transparent, explainable, audit-ready trail. Defensible RAF, not just higher scores.
Agentic AI built for Medicare Advantage and Duals: in-production agents ingest claims, clinical, lab, encounter, and pharmacy data through an interoperability layer and embed directly into existing payer and provider workflows for accurate, consistent HCC capture at scale across prospective and retrospective review.
Human-in-the-lead and secure by attestation: your coders and compliance teams keep clinical judgment while Chiral automates retrieval, MEAT validation, and evidence assembly. HIPAA-compliant, SOC 2 Type II, with a signed BAA, deployed inside your AWS environment so no PHI ever leaves your control.
AWS Marketplace now accepts line of credit payments through the PNC Vendor Finance program. This program is available to select AWS customers in the US, excluding NV, NC, ND, TN, & VT.
Pricing is based on the duration and terms of your contract with the vendor, and additional usage. You pay upfront or in installments according to your contract terms with the vendor. This entitles you to a specified quantity of use for the contract duration. Usage-based pricing is in effect for overages or additional usage not covered in the contract. These charges are applied on top of the contract price. If you choose not to renew or replace your contract before the contract end date, access to your entitlements will expire.
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Designed for organizations evaluating CHIRAL before enterprise deployment. The program includes a fully provisioned CHIRAL workspace, onboarding, standard configuration, and access to core platform capabilities for processing up to 10,000 patient records during the 30-day period.
This listing offers one contract option: a Proof of Value program. You pay for a fixed 30-day evaluation covering up to 10,000 patient records. The price is a single commitment, not a recurring or usage-based charge. It includes a provisioned workspace, onboarding, standard configuration, and access to core platform capabilities. This program is scoped for organizations testing the solution before any enterprise deployment. Pricing does not scale with additional records or add-ons within this dimension; the 10,000-patient cap and 30-day term define the full scope of what you receive.
Top-of-mind questions for buyers
What counts as one patient record toward the 10,000-patient cap?
One patient record is a single patient's set of documentation processed through the platform. This includes charts, claims, and clinical documents tied to that patient. The program covers up to 10,000 such records during the 30-day window. Records beyond that cap fall outside this evaluation scope.
What happens if I reach the 10,000-patient limit before the 30 days end?
The 10,000-patient cap and 30-day term together define the full scope of this program. Processing beyond 10,000 records or past 30 days is not part of this dimension. No additional usage charges scale within it. To process more records, you would move toward enterprise deployment, which is a separate arrangement.
Does this program require EHR integration to process my records?
No. The platform ingests clinical documentation through secure data pipelines and APIs without requiring EHR integration. The Proof of Value program includes a provisioned workspace, onboarding, and standard configuration. This lets you connect existing data sources and process records during the 30-day evaluation.
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60-minute live analyst briefing on the Chiral Chemicals Market (2026–2035), helping specialty chemical and pharmaceutical leaders optimize AWS-cloud roadmaps for predictive manufacturing, R&D intelligence, and supply chain resilience.
The global Chiral Chemicals Market is projected to achieve a substantial size, reaching $149.95 billion by 2030, exhibiting a notable CAGR of 9.8% from 2023 to 2030. The escalating demand for chiral chemicals is fueled by factors including a burgeoning population, shrinking arable land, and the impact of changing climate conditions on food security. This upward trajectory underscores the market's significance in addressing critical challenges and adapting to evolving environmental dynamics.
The global Chiral Chemicals Market is expected to achieve a valuation of $150 billion by 2030, exhibiting a Compound Annual Growth Rate (CAGR) of 10% from 2023 to 2030. The escalating demand for chiral chemicals can be attributed to factors such as the expanding global population, diminishing arable land, and evolving climate conditions affecting food security worldwide.
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