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InterSystems OMOP
InterSystems OMOP creates a seamless process where real-world data extraction, transformation, and loading from diverse EHRs into a managed OMOP repository becomes a catalyst for innovation and collaboration with your research partners.
Reviews (68)
Eric B.
Powerful All-in-One platform, worth the learning curve
Reviewed on Sep 01, 2026
Review provided by G2
What do you like best about the product?
The things I liked the most are the performance, having the multidimensional engine is really fast to read and write even with high data volume and it gets really impressive when compared with relational databases. Also, I'd like to say that it is really multimodel, so you are able to access the same data with SQL, as an object, or using the Globals. For the last thing, the interoperability module is very mature and there's a lot of features ready-made.
What do you dislike about the product?
There are some things about IRIS that bother me a little bit, the small community, when you compare it with other technologies, is very niche. I asked about IRIS to a lot of people and they don't know what it is. Because of that, it is harder to solve very specific problems, sometimes you will have only the answer at old forums. The job market is very limited, it is hard to find someone who has experience with IRIS, and to hire someone and train them takes time. The licensing cost is not very accessible, so only big companies can afford it.
What problems is the product solving and how is that benefiting you?
The built-in interoperability engine has been very important to reduce development time on integration projects. I can use pre-built adapters and visual pipelines to route and transform messages. What took me weeks now takes days.
Computer Software
High performance, seamless integration, and excellent support
Reviewed on Aug 21, 2026
Review provided by G2
What do you like best about the product?
I admire the response speed, especially when dealing with huge volumes of data; it is perfect for integrations and offers excellent assistance and support. Yes, since I started, I’ve more than doubled my profits using InterSystems IRIS!!
What do you dislike about the product?
Migrating from modern systems to learn ObjectScript is a bit of a hassle and requires more time.
What problems is the product solving and how is that benefiting you?
IRIS has a massive focus on the healthcare sector and comes with built-in support for global protocols such as HL7 and FHIR
Aziz C.
Iris’ Data Persistence Is a Game-Changer
Reviewed on Aug 20, 2026
Review provided by G2
What do you like best about the product?
I think IRIS is a really good product overall, even though it can feel a bit complex at times. What I appreciate the most is the data persistence, which has been especially valuable for my use case. It gives me confidence that the data I need will be there when I need it.
The IRIS portal interface is intuitive up to a point and generally easy to navigate. It took some time to get familiar with certain parts of the platform, but once you understand how things are organized, it becomes much easier to work with.
I also really like how straightforward it is to work with integrations. Setting them up and managing them has been a good experience so far, and I haven't had many issues in that area. The overall performance is another strong point for me. The platform feels reliable and performs well during day to day use.
Overall, I think IRIS is a solid product with a good combination of functionality, performance, and reliability. There is definitely a learning curve in some areas, but once you get used to the platform, it becomes much easier to use and provides a lot of value.
The IRIS portal interface is intuitive up to a point and generally easy to navigate. It took some time to get familiar with certain parts of the platform, but once you understand how things are organized, it becomes much easier to work with.
I also really like how straightforward it is to work with integrations. Setting them up and managing them has been a good experience so far, and I haven't had many issues in that area. The overall performance is another strong point for me. The platform feels reliable and performs well during day to day use.
Overall, I think IRIS is a solid product with a good combination of functionality, performance, and reliability. There is definitely a learning curve in some areas, but once you get used to the platform, it becomes much easier to use and provides a lot of value.
What do you dislike about the product?
One of the main challenges for me has been getting answers to questions or finding solutions when something goes wrong. Since IRIS isn’t as widely known or used as some other technologies, it can sometimes be difficult to find relevant information, examples, or people who have faced the same issue before.
The licensing cost can also be a concern, especially for companies that are considering adopting the technology or expanding its use. It can make it harder to justify the investment compared to more widely used alternatives.
That said, I think InterSystems’ AI could make a big difference here. Having AI support built around the platform could make it easier to find answers, understand how things work, and solve problems without having to rely as much on external resources. I think this could significantly reduce the learning curve and make IRIS more approachable for new users.
The licensing cost can also be a concern, especially for companies that are considering adopting the technology or expanding its use. It can make it harder to justify the investment compared to more widely used alternatives.
That said, I think InterSystems’ AI could make a big difference here. Having AI support built around the platform could make it easier to find answers, understand how things work, and solve problems without having to rely as much on external resources. I think this could significantly reduce the learning curve and make IRIS more approachable for new users.
What problems is the product solving and how is that benefiting you?
Please improve the documentation. The current version can be quite confusing and sometimes makes it difficult to understand how certain features work or how to solve a specific problem. It would be really helpful to have clearer explanations, more practical examples, and better organized information. Improving the documentation would make it much easier for new users to get started and for existing users to find answers when they need them.
Benjamin Z.
Robust and High-Performance ERP Platform
Reviewed on Feb 01, 2026
Review provided by G2
What do you like best about the product?
I like that InterSystems IRIS is particularly well-suited for ERP applications requiring reliability, performance, and data consistency. The platform's flexibility facilitates integrations, especially with nginx as a web server and HAProxy as a reverse proxy. Additionally, the initial setup is easy, and the product's security hardening is facilitated by the online documentation.
What do you dislike about the product?
The areas for improvement mainly involve integrations with other platforms.
What problems is the product solving and how is that benefiting you?
We use InterSystems IRIS to manage complex transactional data, develop robust business logic, and expose high-performance APIs, while being well-suited for ERP applications requiring reliability, performance, and data consistency.
Stav B.
Essential Platform with Stellar Support, Steep Learning Curve
Reviewed on Jan 29, 2026
Review provided by G2
What do you like best about the product?
I really appreciate the Worldwide Response Center (WRC) provided by InterSystems IRIS. Their support team is incredibly responsive and knowledgeable, answering every question with great expertise. It feels like having an extension of our own team. The WRC is a game changer, especially in sectors like finance and automotive where downtime isn't an option. I value that we can set the priority of the ticket and, in crisis situations, they provide immediate access to engineers who truly solve the problem.
What do you dislike about the product?
The learning curve can be steep, especially for newer features or complex cloud configurations. While the documentation is extensive, it can sometimes be difficult to find specific examples for advanced scenarios.
What problems is the product solving and how is that benefiting you?
InterSystems IRIS provides high performance and stability, ensuring data consistency and speed for real-time transaction processing. It eliminates downtime, making our ERP robust and responsive.
Nadyan P.
IRIS: An Outstanding All-in-One Toolbox
Reviewed on Jan 15, 2026
Review provided by G2
What do you like best about the product?
InterSystems products, in general, are outstanding, but IRIS has something extra. What I like most is that IRIS feels like a toolbox that brings together the main InterSystems products, such as Caché and Ensemble, all in one place.
What do you dislike about the product?
Overall, the system is great. The only downside I’ve noticed, as a software developer, is the lack of online tutorials and discussions that cover the development process.
What problems is the product solving and how is that benefiting you?
As a developer, I mostly implement solutions in the healthcare area. This field involves all kinds of information, such as patient records, payments, and health tests. The volume of data is huge, and IRIS can handle all of it smoothly.
Willyam M.
Easy AI integration into IRIS and constant updates that evolve the platform
Reviewed on Jan 14, 2026
Review provided by G2
What do you like best about the product?
The easy integration of AI into IRIS greatly facilitates daily work. Another important point is the recurring updates released on the platform, which help keep everything constantly evolving.
What do you dislike about the product?
The learning process is a bit time-consuming and it may take some time until I feel completely comfortable with the use.
What problems is the product solving and how is that benefiting you?
I face various problems related to AI, and due to the ease of using it within the code, it assists me in my day-to-day work. Additionally, the extremely high-performing database also helps me meet my clients' needs.
Daniel s.
Unified Programming and Complete Documentation Facilitate Use
Reviewed on Jan 08, 2026
Review provided by G2
What do you like best about the product?
I find it very useful because of the way it is programmed and the way SQL connections are made, as everything is integrated. The global variables part is also very good, and the documentation is quite complete, making it easy to find what I need.
What do you dislike about the product?
I'm not a big fan of the screen creation part, as I find the ZEN framework a bit complicated to use. Additionally, I miss native resources aimed at Brazil. Another point is that the community is mostly American or European, which makes it even more difficult for those seeking support or specific content for our country.
What problems is the product solving and how is that benefiting you?
The quick creation of tables makes everything much easier, and the ability to create components is also a great differentiator.
George G.
Powerful Out-of-the-Box Components and Effortless Customization
Reviewed on Dec 18, 2025
Review provided by G2
What do you like best about the product?
It works! There are loads of pre-built components that you can use straight out of the box, the data transformations GUI is very simple to use, and if you need to create custom business components, this can be easily done using code. So you can essentially solve all interoperability problems with IRIS.
What do you dislike about the product?
Sometimes the documentation for methods can be non-existent. The documentation may just say the method name, with no explanation on what it does. This means that you may have to look at the underlying code to determine what a particular method does. Which can obviously be time consuming.
What problems is the product solving and how is that benefiting you?
Enabling different healthcare systems to communicate with one another can make a significant difference. If this connectivity helps reduce the time clinicians spend accessing specific sections of your health record, it means they can devote more attention to you, rather than spending valuable time figuring out how to retrieve your data.
Udo L.
Easy Setup, But High License Costs
Reviewed on Dec 15, 2025
Review provided by G2
What do you like best about the product?
I like InterSystems IRIS because it's speedy and easy to program. The freedom with M, a scripting language, lets you do everything with this database. I also think it's the leading IT platform for health. The initial setup was easy as 1 2 3.
What do you dislike about the product?
License costs are very high. If you want to use it on a website because you love the database - but have to pay for it - while other databases are free.
What problems is the product solving and how is that benefiting you?
I use InterSystems IRIS as a quick database because of its speed and ease of programming.