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    InterSystems OMOP

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    InterSystems OMOP creates a seamless process where real-world data extraction, transformation, and loading from diverse EHRs into a managed OMOP repository becomes a catalyst for innovation and collaboration with your research partners.
    4.6

    Overview

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    InterSystems®, a creative data technology provider dedicated to helping customers solve their most critical scalability, interoperability, and speed problems, offers its market leading InterSystems OMOP service through the AWS Cloud Marketplace.

    InterSystems OMOP offers a light-weight, cloud-based data pipeline and management solution combining the standard Fast Healthcare Interoperability Resources (FHIR) of EHRs with InterSystems out-of-the-box transformation to the CDM and a Software as a Service OMOP repository. With this data, you can also take advantage of the Observational Health Data Sciences and Informatics (OHDSI) community and tools to further enhance your research agenda.

    Built on InterSystems IRIS for Health, InterSystems OMOP supports large-scale clinical research and patient data management with:

    • Efficient, Scalable Access to EHR Data: InterSystems OMOP uses the standard Bulk FHIR capabilities of your EHR(s) to update your OMOP repository with newly eligible patient records as often as nightly.
    • Rapid deployment for OHDSI environments: Spin up an OMOP repository and leverage the OHDSI tools, all built on InterSystems IRIS for Health, delivered in minutes in an AWS cloud environment.
    • Timely Data for Trial Recruitment: Frequent data updates allow clinicians and researchers to identify and recruit potential trial participants more rapidly. Reaching out to candidates immediately after care may increase their willingness to participate.
    • Out-of-the-Box EHR to Research Transformation: The no-code data pipeline provides standard mappings from FHIR to the OMOP CDM to transform EHR data into research-grade information and lower your ETL maintenance costs.
    • Continuous Data Quality Monitoring: Data quality dashboards and summary metrics ensure that problems with data quality can be identified and corrected at the source in a timely manner.

    Key features include:

    • Automatically convert and refresh EHR data into OMOP daily, without the need for complex ETL development.
    • Utilize the widely adopted Bulk FHIR standard by EHR vendors.
    • Quickly deploy an OMOP environment with capacity based subscription pricing.
    • Ensure security and regulatory compliance by leveraging cloud vendor best practices.
    • Utilize a data quality dashboard before data transformation to detect and monitor data quality.
    • Enable incremental data refresh for only those patients with new data.
    • Out-of-the-box availability of common terminology mapping to OMOP ontology with support for local terminology mapping.
    • Common FHIR resources are mapped to OMOP out of the box.
    • Integrate IRIS as a new OMOP database option for OHDSI tools as well as sending data to existing OMOP repository.
    • Option to support advanced patient privacy protection.

    The pricing shown is a representative pricing for a typical study configuration. Actual contract pricing is available via private offering.

    Highlights

    • Automated FHIR to OMOP data conversion and daily refresh in secure ephemeral data enclave for research
    • Built in FHIR data quality checks and reports prior to OMOP transformation
    • OHDSI tools run on InterSystems IRIS platform

    Details

    Delivery method

    Deployed on AWS
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    Pricing

    InterSystems OMOP

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    Pricing is based on the duration and terms of your contract with the vendor. This entitles you to a specified quantity of use for the contract duration. If you choose not to renew or replace your contract before it ends, access to these entitlements will expire.
    Additional AWS infrastructure costs may apply. Use the AWS Pricing Calculator  to estimate your infrastructure costs.

    12-month contract (1)

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    Dimension
    Description
    Cost/12 months
    InterSystems OMOP
    Price representative of a 100,000-patient study. Actual contract pricing available via private offer.
    $100,000.00

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    Usage information

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    Delivery details

    Software as a Service (SaaS)

    SaaS delivers cloud-based software applications directly to customers over the internet. You can access these applications through a subscription model. You will pay recurring monthly usage fees through your AWS bill, while AWS handles deployment and infrastructure management, ensuring scalability, reliability, and seamless integration with other AWS services.

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    Vendor support

    InterSystems provides a fast path to get acquainted with our technology, development resources and support. Our Developer Community lets you engage to ask questions and share approaches and solutions. We offer comprehensive online learning courses. Organizations can find the full InterSystems IRIS documentation online, and can rely on enterprise-level support through the iService portal, backed by a 7/24/365 response center.

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    AWS Support is a one-on-one, fast-response support channel that is staffed 24x7x365 with experienced and technical support engineers. The service helps customers of all sizes and technical abilities to successfully utilize the products and features provided by Amazon Web Services.

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    Customer reviews

    Ratings and reviews

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    4.6
    65 ratings
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    65 external reviews
    External reviews are from G2 .
    Stav B.

    Essential Platform with Stellar Support, Steep Learning Curve

    Reviewed on Jan 29, 2026
    Review provided by G2
    What do you like best about the product?
    I really appreciate the Worldwide Response Center (WRC) provided by InterSystems IRIS. Their support team is incredibly responsive and knowledgeable, answering every question with great expertise. It feels like having an extension of our own team. The WRC is a game changer, especially in sectors like finance and automotive where downtime isn't an option. I value that we can set the priority of the ticket and, in crisis situations, they provide immediate access to engineers who truly solve the problem.
    What do you dislike about the product?
    The learning curve can be steep, especially for newer features or complex cloud configurations. While the documentation is extensive, it can sometimes be difficult to find specific examples for advanced scenarios.
    What problems is the product solving and how is that benefiting you?
    InterSystems IRIS provides high performance and stability, ensuring data consistency and speed for real-time transaction processing. It eliminates downtime, making our ERP robust and responsive.
    Nadyan P.

    IRIS: An Outstanding All-in-One Toolbox

    Reviewed on Jan 15, 2026
    Review provided by G2
    What do you like best about the product?
    InterSystems products, in general, are outstanding, but IRIS has something extra. What I like most is that IRIS feels like a toolbox that brings together the main InterSystems products, such as Caché and Ensemble, all in one place.
    What do you dislike about the product?
    Overall, the system is great. The only downside I’ve noticed, as a software developer, is the lack of online tutorials and discussions that cover the development process.
    What problems is the product solving and how is that benefiting you?
    As a developer, I mostly implement solutions in the healthcare area. This field involves all kinds of information, such as patient records, payments, and health tests. The volume of data is huge, and IRIS can handle all of it smoothly.
    Computer Software

    InterSystems IRIS: Integration and Performance in One Place

    Reviewed on Dec 23, 2025
    Review provided by G2
    What do you like best about the product?
    What impresses me most about InterSystems IRIS is the way it solves the problem of technological fragmentation. In many projects, you need a relational database, a cache for performance, a search engine, and an integration tool (ESB) all separately. IRIS puts all of this into a single high-performance "box."
    What do you dislike about the product?
    The steep learning curve of the proprietary ObjectScript language and the smaller community compared to open source technologies are the main technical friction points I observe.
    What problems is the product solving and how is that benefiting you?
    Companies, especially in the healthcare and finance sectors, often deal with dozens of isolated systems that do not communicate with each other. InterSystems IRIS resolves this fragmentation through a robust integration mechanism, with an embedded Enterprise Service Bus, that translates and connects these environments; in healthcare, for example, it natively interprets complex protocols like HL7 and FHIR, allowing laboratories and electronic health records to exchange data in real time. In addition to unifying communication, the platform eliminates delays caused by the common need to separate transactional databases from analytical ones. By acting as a Translytical solution, IRIS can process heavy analytics via SQL or Analytics simultaneously with the ingestion of thousands of transactions per second in the same database, ensuring high performance without bottlenecks.
    George G.

    Powerful Out-of-the-Box Components and Effortless Customization

    Reviewed on Dec 18, 2025
    Review provided by G2
    What do you like best about the product?
    It works! There are loads of pre-built components that you can use straight out of the box, the data transformations GUI is very simple to use, and if you need to create custom business components, this can be easily done using code. So you can essentially solve all interoperability problems with IRIS.
    What do you dislike about the product?
    Sometimes the documentation for methods can be non-existent. The documentation may just say the method name, with no explanation on what it does. This means that you may have to look at the underlying code to determine what a particular method does. Which can obviously be time consuming.
    What problems is the product solving and how is that benefiting you?
    Enabling different healthcare systems to communicate with one another can make a significant difference. If this connectivity helps reduce the time clinicians spend accessing specific sections of your health record, it means they can devote more attention to you, rather than spending valuable time figuring out how to retrieve your data.
    Udo L.

    Easy Setup, But High License Costs

    Reviewed on Dec 15, 2025
    Review provided by G2
    What do you like best about the product?
    I like InterSystems IRIS because it's speedy and easy to program. The freedom with M, a scripting language, lets you do everything with this database. I also think it's the leading IT platform for health. The initial setup was easy as 1 2 3.
    What do you dislike about the product?
    License costs are very high. If you want to use it on a website because you love the database - but have to pay for it - while other databases are free.
    What problems is the product solving and how is that benefiting you?
    I use InterSystems IRIS as a quick database because of its speed and ease of programming.
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