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    InterSystems OMOP

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    InterSystems OMOP creates a seamless process where real-world data extraction, transformation, and loading from diverse EHRs into a managed OMOP repository becomes a catalyst for innovation and collaboration with your research partners.
    4.6

    Overview

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    InterSystems®, a creative data technology provider dedicated to helping customers solve their most critical scalability, interoperability, and speed problems, offers its market leading InterSystems OMOP service through the AWS Cloud Marketplace.

    InterSystems OMOP offers a light-weight, cloud-based data pipeline and management solution combining the standard Fast Healthcare Interoperability Resources (FHIR) of EHRs with InterSystems out-of-the-box transformation to the CDM and a Software as a Service OMOP repository. With this data, you can also take advantage of the Observational Health Data Sciences and Informatics (OHDSI) community and tools to further enhance your research agenda.

    Built on InterSystems IRIS for Health, InterSystems OMOP supports large-scale clinical research and patient data management with:

    • Efficient, Scalable Access to EHR Data: InterSystems OMOP uses the standard Bulk FHIR capabilities of your EHR(s) to update your OMOP repository with newly eligible patient records as often as nightly.
    • Rapid deployment for OHDSI environments: Spin up an OMOP repository and leverage the OHDSI tools, all built on InterSystems IRIS for Health, delivered in minutes in an AWS cloud environment.
    • Timely Data for Trial Recruitment: Frequent data updates allow clinicians and researchers to identify and recruit potential trial participants more rapidly. Reaching out to candidates immediately after care may increase their willingness to participate.
    • Out-of-the-Box EHR to Research Transformation: The no-code data pipeline provides standard mappings from FHIR to the OMOP CDM to transform EHR data into research-grade information and lower your ETL maintenance costs.
    • Continuous Data Quality Monitoring: Data quality dashboards and summary metrics ensure that problems with data quality can be identified and corrected at the source in a timely manner.

    Key features include:

    • Automatically convert and refresh EHR data into OMOP daily, without the need for complex ETL development.
    • Utilize the widely adopted Bulk FHIR standard by EHR vendors.
    • Quickly deploy an OMOP environment with capacity based subscription pricing.
    • Ensure security and regulatory compliance by leveraging cloud vendor best practices.
    • Utilize a data quality dashboard before data transformation to detect and monitor data quality.
    • Enable incremental data refresh for only those patients with new data.
    • Out-of-the-box availability of common terminology mapping to OMOP ontology with support for local terminology mapping.
    • Common FHIR resources are mapped to OMOP out of the box.
    • Integrate IRIS as a new OMOP database option for OHDSI tools as well as sending data to existing OMOP repository.
    • Option to support advanced patient privacy protection.

    The pricing shown is a representative pricing for a typical study configuration. Actual contract pricing is available via private offering.

    Highlights

    • Automated FHIR to OMOP data conversion and daily refresh in secure ephemeral data enclave for research
    • Built in FHIR data quality checks and reports prior to OMOP transformation
    • OHDSI tools run on InterSystems IRIS platform

    Details

    Delivery method

    Deployed on AWS
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    Pricing

    InterSystems OMOP

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    Pricing is based on the duration and terms of your contract with the vendor. This entitles you to a specified quantity of use for the contract duration. If you choose not to renew or replace your contract before it ends, access to these entitlements will expire.
    Additional AWS infrastructure costs may apply. Use the AWS Pricing Calculator  to estimate your infrastructure costs.

    12-month contract (1)

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    Dimension
    Description
    Cost/12 months
    InterSystems OMOP
    Price representative of a 100,000-patient study. Actual contract pricing available via private offer.
    $100,000.00

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    Usage information

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    Software as a Service (SaaS)

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    Vendor support

    InterSystems provides a fast path to get acquainted with our technology, development resources and support. Our Developer Community lets you engage to ask questions and share approaches and solutions. We offer comprehensive online learning courses. Organizations can find the full InterSystems IRIS documentation online, and can rely on enterprise-level support through the iService portal, backed by a 7/24/365 response center.

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    Customer reviews

    Ratings and reviews

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    4.6
    68 ratings
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    68 external reviews
    External reviews are from G2 .
    Benjamin Z.

    Robust and High-Performance ERP Platform

    Reviewed on Feb 01, 2026
    Review provided by G2
    What do you like best about the product?
    I like that InterSystems IRIS is particularly well-suited for ERP applications requiring reliability, performance, and data consistency. The platform's flexibility facilitates integrations, especially with nginx as a web server and HAProxy as a reverse proxy. Additionally, the initial setup is easy, and the product's security hardening is facilitated by the online documentation.
    What do you dislike about the product?
    The areas for improvement mainly involve integrations with other platforms.
    What problems is the product solving and how is that benefiting you?
    We use InterSystems IRIS to manage complex transactional data, develop robust business logic, and expose high-performance APIs, while being well-suited for ERP applications requiring reliability, performance, and data consistency.
    Stav B.

    Essential Platform with Stellar Support, Steep Learning Curve

    Reviewed on Jan 29, 2026
    Review provided by G2
    What do you like best about the product?
    I really appreciate the Worldwide Response Center (WRC) provided by InterSystems IRIS. Their support team is incredibly responsive and knowledgeable, answering every question with great expertise. It feels like having an extension of our own team. The WRC is a game changer, especially in sectors like finance and automotive where downtime isn't an option. I value that we can set the priority of the ticket and, in crisis situations, they provide immediate access to engineers who truly solve the problem.
    What do you dislike about the product?
    The learning curve can be steep, especially for newer features or complex cloud configurations. While the documentation is extensive, it can sometimes be difficult to find specific examples for advanced scenarios.
    What problems is the product solving and how is that benefiting you?
    InterSystems IRIS provides high performance and stability, ensuring data consistency and speed for real-time transaction processing. It eliminates downtime, making our ERP robust and responsive.
    Nadyan P.

    IRIS: An Outstanding All-in-One Toolbox

    Reviewed on Jan 15, 2026
    Review provided by G2
    What do you like best about the product?
    InterSystems products, in general, are outstanding, but IRIS has something extra. What I like most is that IRIS feels like a toolbox that brings together the main InterSystems products, such as Caché and Ensemble, all in one place.
    What do you dislike about the product?
    Overall, the system is great. The only downside I’ve noticed, as a software developer, is the lack of online tutorials and discussions that cover the development process.
    What problems is the product solving and how is that benefiting you?
    As a developer, I mostly implement solutions in the healthcare area. This field involves all kinds of information, such as patient records, payments, and health tests. The volume of data is huge, and IRIS can handle all of it smoothly.
    Willyam M.

    Easy AI integration into IRIS and constant updates that evolve the platform

    Reviewed on Jan 14, 2026
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    What do you like best about the product?
    The easy integration of AI into IRIS greatly facilitates daily work. Another important point is the recurring updates released on the platform, which help keep everything constantly evolving.
    What do you dislike about the product?
    The learning process is a bit time-consuming and it may take some time until I feel completely comfortable with the use.
    What problems is the product solving and how is that benefiting you?
    I face various problems related to AI, and due to the ease of using it within the code, it assists me in my day-to-day work. Additionally, the extremely high-performing database also helps me meet my clients' needs.
    Daniel s.

    Unified Programming and Complete Documentation Facilitate Use

    Reviewed on Jan 08, 2026
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    What do you like best about the product?
    I find it very useful because of the way it is programmed and the way SQL connections are made, as everything is integrated. The global variables part is also very good, and the documentation is quite complete, making it easy to find what I need.
    What do you dislike about the product?
    I'm not a big fan of the screen creation part, as I find the ZEN framework a bit complicated to use. Additionally, I miss native resources aimed at Brazil. Another point is that the community is mostly American or European, which makes it even more difficult for those seeking support or specific content for our country.
    What problems is the product solving and how is that benefiting you?
    The quick creation of tables makes everything much easier, and the ability to create components is also a great differentiator.
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