Sold by: Sage Bionetworks
Open data
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Deployed on AWS
The UKB-PPP is a collaboration between the UK Biobank (UKB) and thirteen biopharmaceutical companies characterising the plasma proteomic profiles of 54,219 UKB participants. As part of a collaborative analysis across the thirteen UKB-PPP partners, we conducted comprehensive protein quantitative trait loci (pQTL) mapping of 2,923 proteins that identifies 14,287 primary genetic associations, of which 85% are newly discovered, in addition to ancestry-specific pQTL mapping in non-Europeans. We identify independent secondary associations in 87% of cis and 30% of trans loci, expanding the catalogue of genetic instruments for downstream analyses.
Overview
The UKB-PPP is a collaboration between the UK Biobank (UKB) and thirteen biopharmaceutical companies characterising the plasma proteomic profiles of 54,219 UKB participants. As part of a collaborative analysis across the thirteen UKB-PPP partners, we conducted comprehensive protein quantitative trait loci (pQTL) mapping of 2,923 proteins that identifies 14,287 primary genetic associations, of which 85% are newly discovered, in addition to ancestry-specific pQTL mapping in non-Europeans. We identify independent secondary associations in 87% of cis and 30% of trans loci, expanding the catalogue of genetic instruments for downstream analyses.
Features and programs
Open Data Sponsorship Program
This dataset is part of the Open Data Sponsorship Program, an AWS program that covers the cost of storage for publicly available high-value cloud-optimized datasets.
Pricing
This is a publicly available data set. No subscription is required.
Legal
Content disclaimer
Vendors are responsible for their product descriptions and other product content. AWS does not warrant that vendors' product descriptions or other product content are accurate, complete, reliable, current, or error-free.
Delivery details
AWS Data Exchange (ADX)
AWS Data Exchange is a service that helps AWS easily share and manage data entitlements from other organizations at scale.
Open data resources
Available with or without an AWS account.
- How to use
- To access these resources, reference the Amazon Resource Name (ARN) using the AWS Command Line Interface (CLI). Learn more
- Description
- Population-specific GWAS summary statistics per protein measurement, as well as meta-data for annotating protein measurements and genetic variants.
- Resource type
- S3 bucket
- Amazon Resource Name (ARN)
- arn:aws:s3:::ukbiobank.opendata.sagebase.org
- AWS region
- us-east-1
- AWS CLI access (No AWS account required)
- aws s3 ls --no-sign-request s3://ukbiobank.opendata.sagebase.org/
Resources
Vendor resources
Support
Managed By
Sage Bionetworks
How to cite
UK Biobank Pharma Proteomics Project (UKB-PPP) was accessed on DATE from https://registry.opendata.aws/ukbppp .
License
[CC BY]
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