Sold by: Salk Institute
Open data
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Deployed on AWS
Aging is a major risk factor for neurodegenerative diseases, yet underlying epigenetic mechanisms remain unclear. Here, we generated a comprehensive single-nucleus cell atlas of brain aging across multiple brain regions, comprising 132,551 single-cell methylomes and 72,666 joint chromatin conformation-methylome nuclei. Integration with companion transcriptomic and chromatin accessibility data yielded a cross-modality taxonomy of 36 major cell types.
Overview
Aging is a major risk factor for neurodegenerative diseases, yet underlying epigenetic mechanisms remain unclear. Here, we generated a comprehensive single-nucleus cell atlas of brain aging across multiple brain regions, comprising 132,551 single-cell methylomes and 72,666 joint chromatin conformation-methylome nuclei. Integration with companion transcriptomic and chromatin accessibility data yielded a cross-modality taxonomy of 36 major cell types.
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Open Data Sponsorship Program
This dataset is part of the Open Data Sponsorship Program, an AWS program that covers the cost of storage for publicly available high-value cloud-optimized datasets.
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- How to use
- To access these resources, reference the Amazon Resource Name (ARN) using the AWS Command Line Interface (CLI). Learn more
- Description
- Aging mouse brain epigenomics dataset
- Resource type
- S3 bucket
- Amazon Resource Name (ARN)
- arn:aws:s3:::salk-aging-mouse-brain-epigenetics
- AWS region
- us-west-2
- AWS CLI access (No AWS account required)
- aws s3 ls --no-sign-request s3://salk-aging-mouse-brain-epigenetics/
- Description
- Dataset update notifications
- Resource type
- SNS topic
- Amazon Resource Name (ARN)
- arn:aws:sns:us-west-2:855738613743:salk-aging-mouse-brain-epigenetics-updates
- AWS region
- us-west-2
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Aging Mouse Brain Epigenetic was accessed on DATE from https://registry.opendata.aws/salk-aging-mouse-brain-epigeneti .
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