Open data
    |
    Deployed on AWS
    ProteinGym is a benchmark suite for assessing the performance of protein fitness prediction and design models. It comprises a large curated collection of 200+ high-throughput experimental assays (~3M mutated sequences), as well as clinical annotations from experts about the pathogenicity of mutants in over 3k human genes.

    Overview

    ProteinGym is a benchmark suite for assessing the performance of protein fitness prediction and design models. It comprises a large curated collection of 200+ high-throughput experimental assays (~3M mutated sequences), as well as clinical annotations from experts about the pathogenicity of mutants in over 3k human genes.

    Features and programs

    Open Data Sponsorship Program

    This dataset is part of the Open Data Sponsorship Program, an AWS program that covers the cost of storage for publicly available high-value cloud-optimized datasets.

    Pricing

    This is a publicly available data set. No subscription is required.

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    Usage information

     Info

    Delivery details

    AWS Data Exchange (ADX)

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    Open data resources

    Available with or without an AWS account.

    How to use
    To access these resources, reference the Amazon Resource Name (ARN) using the AWS Command Line Interface (CLI). Learn more 
    Description
    ProteinGym dataset including all substitution/indel mutations from Deep Mutational Scanning (DMS) experiments (DMS_substitutions.parquet / DMS_indels.parquet), and all substitution/indel mutations from clinical variant databases (clinical_substitutions.parquet / clinical_indels.parquet).
    Resource type
    S3 bucket
    Amazon Resource Name (ARN)
    arn:aws:s3:::proteingym
    AWS region
    us-east-2
    AWS CLI access (No AWS account required)
    aws s3 ls --no-sign-request s3://proteingym/

    Resources

    Support

    Managed By

    Harvard Medical School, University of Oxford

    How to cite

    ProteinGym was accessed on DATE from https://registry.opendata.aws/proteingym .

    License

    MIT License