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The Seattle Alzheimer's Disease Brain Cell Atlas Integrative Analysis Center
(SEA-AD IAC) reprocesses datasets from SEA-AD and other large-scale
Alzheimer's disease and related dementia studies to support harmonized
cross-study analyses. The study provides uniformly processed single-cell
genomics and multiomic data, harmonized metadata, and representations of
disease pathology mapped to highly annotated BRAIN Initiative Cell Atlas
Network (BICAN) and SEA-AD cell classifications. These resources support
investigation of cell-type-specific molecular changes across Alzheimer's
disease cohorts and stages of disease progression.
Overview
The Seattle Alzheimer's Disease Brain Cell Atlas Integrative Analysis Center (SEA-AD IAC) reprocesses datasets from SEA-AD and other large-scale Alzheimer's disease and related dementia studies to support harmonized cross-study analyses. The study provides uniformly processed single-cell genomics and multiomic data, harmonized metadata, and representations of disease pathology mapped to highly annotated BRAIN Initiative Cell Atlas Network (BICAN) and SEA-AD cell classifications. These resources support investigation of cell-type-specific molecular changes across Alzheimer's disease cohorts and stages of disease progression.
Features and programs
Open Data Sponsorship Program
This dataset is part of the Open Data Sponsorship Program, an AWS program that covers the cost of storage for publicly available high-value cloud-optimized datasets.
Pricing
This is a publicly available data set. No subscription is required.
Legal
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Delivery details
AWS Data Exchange (ADX)
AWS Data Exchange is a service that helps AWS easily share and manage data entitlements from other organizations at scale.
Open data resources
Available with or without an AWS account.
- How to use
- To access these resources, reference the Amazon Resource Name (ARN) using the AWS Command Line Interface (CLI). Learn more
- Description
- This study provides controlled-access, uniformly reprocessed single-nucleus RNA sequencing and multiomic data, harmonized metadata, cell-type classifications, and associated representations of Alzheimer's disease pathology from SEA-AD and other community studies.
- Resource type
- S3 bucket
- Amazon Resource Name (ARN)
- arn:aws:s3:::sea-ad-iac.opendata.sagebase.org
- AWS region
- us-east-1
- AWS CLI access (No AWS account required)
- aws s3 ls --no-sign-request s3://sea-ad-iac.opendata.sagebase.org/
Resources
Vendor resources
Support
Managed By
Sage Bionetworks
How to cite
The SEA-AD Integrative Analysis Center Study (SEA-AD IAC) was accessed on DATE from https://registry.opendata.aws/sea-ad-iac .
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