We have deployed the solution on VMware, private cloud, and public cloud. F5 is going to release a new product, BIG-IP Next, which will be a new implementation of BIG-IP with many more features. BIG-IP Next is going to be more cloud-friendly because it's going to be based on containers.
F5 BIG-IP Virtual Edition has a scripting module. If something is not in the default functionality, you could always make a script that will solve your issue. Even if it's something that would take a week, you'll still be able to write a script to solve your custom use case. Most vendors don't have such scripting functionality.
F5 BIG-IP Virtual Edition is worth it, but it's a complex solution that has many functions. Users may have to do some learning instead of using it straight away. The learning material is publicly available to learn, but it will take time.
The solution's integration is straightforward because it integrates well with others like Splunk. The solution's security functionality is one of the best for the on-premises device. Nowadays, the solution has integration with shared security.
Overall, I rate the solution a nine out of ten.