Sold by: OpenFold
Open data
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Deployed on AWS
Multiple sequence alignments (MSAs) for 140,000 unique [Protein Data Bank](https://www.rcsb.org/) (PDB) chains and 16,000,000 [UniClust30](https://uniclust.mmseqs.com/) clusters. Template hits are also provided for the PDB chains and 270,000 UniClust30 clusters chosen for maximal diversity and MSA depth. MSAs were generated with HHBlits (-n3) and JackHMMER against MGnify, BFD, UniRef90, and UniClust30 while templates were identified from PDB70 with HHSearch, all according to procedures outlined in the supplement to the AlphaFold 2 Nature paper, [Jumper et al. 2021](https://www.nature.com/articles/s41586-021-03819-2). We expect the database to be broadly useful to structural biologists training or validating deep learning models for protein structure prediction and related tasks.
Overview
Multiple sequence alignments (MSAs) for 140,000 unique Protein Data Bank (PDB) chains and 16,000,000 UniClust30 clusters. Template hits are also provided for the PDB chains and 270,000 UniClust30 clusters chosen for maximal diversity and MSA depth. MSAs were generated with HHBlits (-n3) and JackHMMER against MGnify, BFD, UniRef90, and UniClust30 while templates were identified from PDB70 with HHSearch, all according to procedures outlined in the supplement to the AlphaFold 2 Nature paper, Jumper et al. 2021 . We expect the database to be broadly useful to structural biologists training or validating deep learning models for protein structure prediction and related tasks.
Features and programs
Open Data Sponsorship Program
This dataset is part of the Open Data Sponsorship Program, an AWS program that covers the cost of storage for publicly available high-value cloud-optimized datasets.
Pricing
This is a publicly available data set. No subscription is required.
Legal
Content disclaimer
Vendors are responsible for their product descriptions and other product content. AWS does not warrant that vendors' product descriptions or other product content are accurate, complete, reliable, current, or error-free.
Delivery details
AWS Data Exchange (ADX)
AWS Data Exchange is a service that helps AWS easily share and manage data entitlements from other organizations at scale.
Open data resources
Available with or without an AWS account.
- How to use
- To access these resources, reference the Amazon Resource Name (ARN) using the AWS Command Line Interface (CLI). Learn more
- Description
- A repository of MSAs and template hits.
- Resource type
- S3 bucket
- Amazon Resource Name (ARN)
- arn:aws:s3:::openfold
- AWS region
- us-east-1
- AWS CLI access (No AWS account required)
- aws s3 ls --no-sign-request s3://openfold/
Resources
Vendor resources
Support
Managed By
OpenFold
How to cite
OpenProteinSet was accessed on DATE from https://registry.opendata.aws/openfold .