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About AWS Open Data Sponsorship Program

This program exists to help people discover and share data sets that are available by using AWS resources. Unless specifically stated in the applicable data set documentation, data sets available through the Registry of Open Data on AWS are not provided or maintained by AWS. Data sets are provided and maintained by a variety of third parties under a variety of licenses. Please check data set licenses and related documentation to determine if a data set may be used for you application. If you have a project using a listed data set please tell us about it at opendata@amazon.com.

AWS Open Data Sponsorship Program

AWS Open Data Sponsorship Program Products (321)
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The Cancer Genome Atlas

Free | Publicly available

The Cancer Genome Atlas (TCGA), a collaboration between the National Cancer Institute (NCI) and National Human Genome Research Institute (NHGRI), aims to generate comprehensive, multi-dimensional maps of the key genomic changes in major types and subtypes of cancer. TCGA has analyzed matched tumor and normal tissues from 11,000 patients, allowing for the comprehensive characterization of 33 cancer types and subtypes, including 10 rare cancers. The dataset contains open Clinical Supplement, Biospecimen Supplement, RNA-Seq Gene Expression Quantification, miRNA-Seq Isoform Expression Quantification, miRNA Expression Quantification, Genotyping Array Copy Number Segment, Genotyping Array Masked Copy Number Segment, Genotyping Array Gene Level Copy Number Scores, and WXS Masked Somatic Mutation data from Genomic Data Commons (GDC). This dataset also contains controlled Whole Exome Sequencing (WXS), RNA-Seq, miRNA-Seq, ATAC-Seq Aligned Reads, WXS Annotated Somatic Mutation, WXS Raw Somat[...]

NIH NCBI Sequence Read Archive (SRA) on AWS

Free | Publicly available

The Sequence Read Archive (SRA), produced by the National Center for Biotechnology Information (NCBI) at the National Library of Medicine (NLM) at the National Institutes of Health (NIH), stores raw DNA sequencing data and alignment information from high-throughput sequencing platforms. The SRA provides open access to these biological sequence data to support the research community's efforts to enhance reproducibility and make new discoveries by comparing data sets. Buckets in this registry contain public SRA data in the original (user submitted) format from select high value and newly-released studies as well as all public-access SRA formatted ETL+BQS data. Also included is all SRA metadata that can be leveraged for attribute-based data discovery.

Cancer Cell Line Encyclopedia (CCLE)

Free | Publicly available

The Cancer Cell Line Encyclopedia (CCLE) project is an effort to conduct a detailed genetic characterization of a large panel of human cancer cell lines. The CCLE provides public access to genomic data, visualization and analysis for over 1100 cancer cell lines. This dataset contains RNA-Seq Aligned Reads, WXS Aligned Reads, and WGS Aligned Reads data.

Cell Painting Image Collection

Free | Publicly available

The Cell Painting Image Collection is a collection of freely downloadable microscopy image sets. Cell Painting is an unbiased high throughput imaging assay used to analyze perturbations in cell models. In addition to the images themselves, each set includes a description of the biological application and some type of "ground truth" (expected results). Researchers are encouraged to use these image sets as reference points when developing, testing, and publishing new image analysis algorithms for the life sciences. We hope that the this data set will lead to a better understanding of which methods are best for various biological image analysis applications.

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