Quantum optimization is an expanding field with several applications and significant potential business benefits. MegaQUBO is an accelerator for Quantum Optimization projects specifically designed to solve large Quadratic Unconstrained Binary Optimization (QUBO) problems in a reduced amount of time. MegaQUBO solves the optimization problems by leveraging GPUs’ (Graphics Processing Units) massive parallelization capabilities or, through efficient decomposition strategies, Quantum Processing Units (QPUs). When compared to alternative solvers, MegaQUBO speeds up business processes while providing optimization solutions with a significantly high quality, which is reflected on the enhanced values achieved in the corresponding Key Performance Indicators (KPIs). In addition, MegaQUBO offers an interactive dashboard providing a series of functionalities, such as: the monitoring of the health of the system and current scaling capability, the management of different models and their versioning, the execution of different elaboration runs and the respective state, the possibility to directly download specific solutions computed in the past and the fine tuning of different solvers’ parameters. Finally, it is possible to easily use MegaQUBO thanks to its AWS cloud deployment, which features a complete installation and is accessible through an authentication method that requires only an activation of a username and password.