Tag: HPC

Understanding deal and portfolio risk and capital requirements is a computationally expensive process that requires the execution of multiple financial forecasting models every day and in often in real time. This post describes how it works at RenaissanceRe, one of the world’s leading reinsurance companies.

In this blog post, we discuss the AWS solution that Amazon’s construction division used to conduct large-scale CFD fire simulations as part of their Fire Strategy solutions to demonstrate safety and fire mitigation strategies. We outline the five key steps taken that resulted in simulation times that were 15-20x faster than previous on-premises architectures, reducing the time to complete from up to twenty-one days to less than one day.

AWS ParallelCluster version 3.2 introduces support for two new Amazon FSx filesystem types (NetApp ONTAP and OpenZFS). It also lifts the limit on the number of filesystem mounts you can have on your cluster. We’ll show you how, and help you with the details for getting this going right away.

AWS ParallelCluster version 3.2 now supports memory-aware scheduling in Slurm to give you control over the placement of jobs with specific memory requirements. In this blog post, we’ll show you how it works, and explain why this will be really useful to people with memory-hungry workloads.

Lawrence Livermore National Laboratory (LLNL) and AWS are joining forces to provide a training opportunity for emerging HPC tools and application. RADIUSS (Rapid Application Development via an Institutional Universal Software Stack) is a broad suite of open-source software projects originating from LLNL. Together we are hosting a tutorial series to give attendees hands-on experience with these cutting-edge technologies. Find out how to participate in these events in this blog post.

In this blog post, we demonstrate how to leverage the AWS Genomics Command line and Amazon SageMaker to analyze large-scale exome sequences and derive meaningful insights. We use the bioinformatics workflow manager Nextflow, it’s open source library of pipelines, NF-Core, and AWS Batch.

In this blog post, we’ll walk you through the process of building a successful Cryo-EM benchmarking pilot using AWS ParallelCluster, Amazon FSx for Lustre, and cryoSPARC (from Structura Biotechnology) and explain some of our design decisions along the way.

In this blog post, we’ll show how you can run NVIDIA Parabricks on AWS Batch leveraging AWS CloudFormation templates. Parabricks is a GPU-accelerated tool for secondary genomic analysis. It reduces the runtime of variant calling on a 30x human genome from 30 hours to just 30 minutes, and leverages AWS Batch to provide an interface that scales compute jobs across multiple instances in the cloud.

Somatic variants are genetic alterations which are not inherited but acquired during one’s lifespan, for example those that are present in cancer tumors. In this post, we will demonstrate how to perform somatic variant calling from matched tumor and normal genome sequence data, as well as tumor-only whole genome and whole exome datasets using an NVIDIA GPU-accelerated Parabricks pipeline, and compare the results with baseline CPU-based workflows.

Organizations such as Amazon Prime Air and Joby Aviation use Simcenter STAR-CCM+ for running CFD simulations on AWS so they can reduce product manufacturing cycles and achieve faster times to market. In this post today, we describe the performance and price analysis of running Computational Fluid Dynamics (CFD) simulations using Siemens SimcenterTM STAR-CCM+TM software on AWS HPC clusters.