AWS HPC Blog

Tag: HPC

High Throughput Scheduling for Financial Services with YellowDog HTS on AWS

This post was contributed by Kirill Bogdanov (Pr. Solutions Architect at AWS) and Alan Parry, (CTO at YellowDog). Large-scale compute grids sit at the heart of modern financial services operations. They power overnight batch runs for regulatory risk and prepare traders for the coming day. During trading, the same grids drive intraday ‘value at risk’ […]

Cost-effective and scalable Oxford Nanopore Technologies primary analysis with Nextflow and Amazon EC2 G Instances

This post was contributed by Stefan Dittforth and Michael Mueller Introduction Oxford Nanopore Technologies (ONT) sequencing enhances genome analysis in research and healthcare with its ability to produce long-read sequencing data in real-time. Long reads improve our ability to detect structural variation, resolve repetitive regions, perform haplotype phasing and analyze full-length transcripts, providing a more […]

Accelerating HPC Deployment with AWS Parallel Computing Service and Kiro CLI

Research teams moving from on-premises HPC environments often struggle with the complexity of cloud deployment. Traditional approaches require deep expertise in AWS networking, storage architectures, and Slurm configuration management. A typical manual deployment involves weeks of infrastructure provisioning, network topology design, scheduler configuration, and performance tuning. Research teams with limited platform engineering resources find themselves […]

A Technical Deep Dive into Amazon EC2 Hpc8a Performance for Engineering and Scientific Workloads

High performance computing (HPC) workloads continue to grow in scale and complexity. Whether simulating airflow over an aircraft wing, modeling structural behavior under load, or performing crash simulation and multi-physics analysis, these workloads demand sustained compute throughput, high memory bandwidth, and efficient scaling across large clusters. Improvements in any one of these dimensions can reduce […]

Scaling life sciences research by deploying AWS ParallelCluster and AWS DataSync

In life sciences research, managing large-scale computational resources and data efficiently is important for success. However, traditional on-premises environments often struggle to meet these requirements effectively. This post demonstrates how JSR Corporation transformed their research infrastructure using AWS ParallelCluster and AWS DataSync, achieving a 33% reduction in CPU usage and 85% in storage requirements. JSR’s […]

How Aionics accelerates chemical formulation and discovery with AWS Parallel Computing Service

This post was contributed by Mohamed K. Elshazly, PhD, Kareem Abdol-Hamid, Sam Bydlon, PhD, Aarabhi Achanta, and Mark Azadpour The decarbonization of our modern economy depends on solving a defining scientific challenge: developing batteries that are both safe and high performing. From electrical grids to vehicles and aviation, these energy storage devices must provide power […]

How Proteros accelerates drug discovery by using AWS ParallelCluster

Proteros is a leader in structure-based drug discovery solutions, and supports pharmaceutical, biotechnological, and academic clients with advanced technologies like Cryogenic Electron Microscopy (Cryo-EM) and Protein Crystallography (PX). In this blog post, we’ll explore how Proteros implemented an HPC solution that scales with their scientific ambitions. We’ll talk about how they started with a secure […]

How Daiichi Sankyo modernized drug discovery using AWS Parallel Computing Service

This blog was co-authored by Takehiro Nakajima and Mark Azadpour from AWS and Rintaro Yamada, Rei Kajitani and Ryo Kunimoto from Daiichi Sankyo In recent years, the informatics field of drug discovery has seen a rapid increase in workloads requiring large-scale parallel computing, such as genome analysis, structure prediction, and drug design. Daiichi Sankyo has […]

AWS at SC25 - Meet the Advanced Computing team at Booth #2207

Meet the Advanced Computing team of AWS at SC25 in St. Louis

We want to empower every scientist and engineer to solve hard problems by giving them access to the compute and analytical tools they need, when they need them. Cloud HPC can be a real human progress catalyst. If you run large scale simulations, tune complex models, or support researchers who consistently need more compute, the […]

AWS re:Invent 2025: Your Complete Guide to High Performance Computing Sessions

AWS re:Invent 2025 returns to Las Vegas, Nevada on December 1, uniting AWS builders, customers, partners, and IT professionals from across the globe. This year’s event offers you exclusive access to compelling customer stories and insights from AWS leadership as they tackle today’s most critical challenges in high-performance computing, from accelerating scientific discovery to optimizing […]